🧬 Mark Kotter - bit.bio - Part 2 | Navigating Between the Clinical & Research Worlds | Lessons in Combining Different Fields | The Evolution of Cell Therapies | Transitioning from Academia to Entrepreneurship

The Biotech Startups Podcast

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เนื้อหาจัดทำโดย Jon Chee เนื้อหาพอดแคสต์ทั้งหมด รวมถึงตอน กราฟิก และคำอธิบายพอดแคสต์ได้รับการอัปโหลดและจัดหาให้โดยตรงจาก Jon Chee หรือพันธมิตรแพลตฟอร์มพอดแคสต์ของพวกเขา หากคุณเชื่อว่ามีบุคคลอื่นใช้งานที่มีลิขสิทธิ์ของคุณโดยไม่ได้รับอนุญาต คุณสามารถปฏิบัติตามขั้นตอนที่แสดงไว้ที่นี่ https://th.player.fm/legal

Action Academy | Replace The Job You Hate With A Life You Love

1
How To Replace A $100,000+ Salary Within 6 MONTHS Through Buying A Small Business w/ Alex Kamenca & Carley Mitus 57:50

52 weeksที่แล้ว57:50

ลิสต์เล่นในภายหลัง

ลิสต์

ถูกใจ

ที่ถูกใจแล้ว

57:50

Alex (@alex_kamenca) and Carley (@carleymitus) are both members of our Action Academy Community that purchased TWO small businesses last thursday! Want To Quit Your Job In The Next 6-18 Months Through Buying Commercial Real Estate & Small Businesses? 👔🏝️ Schedule A Free 15 Minute Coaching Call With Our Team Here To Get "Unstuck" Want to know which investment strategy is best for you? Take our Free Asset-Selection Quiz Check Out Our Bestselling Book : From Passive To Passionate : How To Quit Your Job - Grow Your Wealth - And Turn Your Passions Into Profits Want A Free $100k+ Side Hustle Guide ? Follow Me As I Travel & Build: IG @brianluebben ActionAcademy.com…

ประมาณหนึ่งปีที่แล้ว 23:05

MP3•หน้าโฮมของตอน

As a podcast listener, you can redeem exclusive discounts with a growing list of biotech vendors and get $500 off your first equipment lease by using promo code “TBSP” on https://www.excedr.com/rewards.

Part 2 of 4.

My guest today is Mark Kotter, neurosurgeon, stem cell biologist, and CEO and Founder of bit.bio. Bit.bio is an award-winning human synthetic biology company providing human cells for research, drug discovery and cell therapy.

Bit.bio applies a patented safe harbor gene-targeting approach to inducibly express transcription factor combinations that reprogram human induced pluripotent stem cells into highly defined and mature human cell types.

In addition to bit.bio, Mark is also the Co-Founder of Meatable, Scientific Founder and Chairman of rejuvenation start-up clock.bio, and Co-Founder and trustee of Myelopathy.org, the first charity dedicated to a common yet often overseen condition causing a “slow motion spinal cord injury.”

Mark has also been a professor and researcher at Cambridge for more than 15 years. His diverse experience as an academic and serial entrepreneur offers a wealth of insights aspiring scientist-founders can draw from.

Join us this week and hear about Mark’s:

Transition from his PhD studies at Cambridge to the Medical University of Vienna, where he became a resident in neurosurgery and ran his own research group
Experience at the Max Planck Institute for Experimental Medicine
Return to Cambridge, where he combined clinical practice with research
Shift from academia to entrepreneurship, which led to the founding of his first biotech startup

Please enjoy my conversation with Mark Kotter.

Timestamps:

00:28 Intro

01:54 Mark’s spinal cord injury research in Vienna, setting up a lab, and avoiding rigid hierarchy

03:26 Working at the Max Planck Institute, getting noticed again at Cambridge

04:34 Going from no supervisor to teaching PhD students while running a lab

05:36 Starting a new role at Cambridge, the impact of sharing information

08:11 Two different worlds: the research world and the clinical world

09:57 The value of being exposed to and combining the newest tech and patient samples

11:37 Complexity around protocols, cell programming history, and contradictory data

14:18 The translation gap between research and the clinic

16:34 Juggling a teaching role at Cambridge while conducting research, studying in Toronto

18:56 Shifting to the startup world from academia and clinical research

20:23 Starting a family business, understanding financial models and cash flow

21:58 Outro

Enriched Notes:

Topics Mentioned:

Max Planck Institute for Experimental Medicine https://maxplanckneuroscience.org/institute/mpi-exp-medicine/

University of Cambridge https://www.cam.ac.uk/

Neurosurgery https://www.ohsu.edu/school-of-medicine/neurosurgery/what-neurosurgery

Cell Programing https://youtu.be/jrVQXHmxH7Y?si=csFYmCfaqkQFm95y

Differentiation Protocols https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405110/

Direct reprogramming protocols https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161510/

Synthetic Biology https://en.wikipedia.org/wiki/Synthetic_biology

Opti-ox Technology https://www.bit.bio/platform

How to Spin Out of Academia https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startup

People Mentioned:

Roger Pedersen https://www.linkedin.com/in/roger-pedersen-0b231115/

Harold Weintraub https://en.wikipedia.org/wiki/Harold_M._Weintraub

Marius Wernig https://med.stanford.edu/profiles/marius-wernig

Thomas Südhof https://med.stanford.edu/sudhoflab/about-thomas-sudhof.html

Shinya Yamanaka https://en.wikipedia.org/wiki/Shinya_Yamanaka

The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.

140 ตอน

#Science #Biology #Business #Jon Chee #Biotech Startups #Biotech #Startup #Excedr #Life Sciences #Entrepreneur #Founders #Culture

🧬 Mark Kotter - bit.bio - Part 2 | Navigating Between the Clinical & Research Worlds | Lessons in Combining Different Fields | The Evolution of Cell Therapies | Transitioning from Academia to Entrepreneurship

The Biotech Startups Podcast

published ประมาณหนึ่งปีที่แล้ว

แบ่งปัน

MP3•หน้าโฮมของตอน

Part 2 of 4.

Join us this week and hear about Mark’s:

Transition from his PhD studies at Cambridge to the Medical University of Vienna, where he became a resident in neurosurgery and ran his own research group
Experience at the Max Planck Institute for Experimental Medicine
Return to Cambridge, where he combined clinical practice with research
Shift from academia to entrepreneurship, which led to the founding of his first biotech startup

Please enjoy my conversation with Mark Kotter.

Timestamps:

00:28 Intro

01:54 Mark’s spinal cord injury research in Vienna, setting up a lab, and avoiding rigid hierarchy

03:26 Working at the Max Planck Institute, getting noticed again at Cambridge

04:34 Going from no supervisor to teaching PhD students while running a lab

05:36 Starting a new role at Cambridge, the impact of sharing information

08:11 Two different worlds: the research world and the clinical world

09:57 The value of being exposed to and combining the newest tech and patient samples

11:37 Complexity around protocols, cell programming history, and contradictory data

14:18 The translation gap between research and the clinic

16:34 Juggling a teaching role at Cambridge while conducting research, studying in Toronto

18:56 Shifting to the startup world from academia and clinical research

20:23 Starting a family business, understanding financial models and cash flow

21:58 Outro

Enriched Notes:

Topics Mentioned:

Max Planck Institute for Experimental Medicine https://maxplanckneuroscience.org/institute/mpi-exp-medicine/

University of Cambridge https://www.cam.ac.uk/

Neurosurgery https://www.ohsu.edu/school-of-medicine/neurosurgery/what-neurosurgery

Cell Programing https://youtu.be/jrVQXHmxH7Y?si=csFYmCfaqkQFm95y

Differentiation Protocols https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405110/

Direct reprogramming protocols https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161510/

Synthetic Biology https://en.wikipedia.org/wiki/Synthetic_biology

Opti-ox Technology https://www.bit.bio/platform

How to Spin Out of Academia https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startup

People Mentioned:

Roger Pedersen https://www.linkedin.com/in/roger-pedersen-0b231115/

Harold Weintraub https://en.wikipedia.org/wiki/Harold_M._Weintraub

Marius Wernig https://med.stanford.edu/profiles/marius-wernig

Thomas Südhof https://med.stanford.edu/sudhoflab/about-thomas-sudhof.html

Shinya Yamanaka https://en.wikipedia.org/wiki/Shinya_Yamanaka

140 ตอน

#Science #Biology #Business #Jon Chee #Biotech Startups #Biotech #Startup #Excedr #Life Sciences #Entrepreneur #Founders #Culture

Minden epizód

The Biotech Startups Podcast

1
🧬 Redefining Biotech: Building Enduring Value Beyond Acquisition | Rabia Khan (Part 4/4) 48:44

1 dayที่แล้ว48:44

48:44

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "If you are that person, if you feel like you can't find your box and you're off doing these random things that no one else seems to find interesting, it's okay. Embrace it. It's who you are and it's going to be your superpower someday." In this episode of The Biotech Startups Podcast , host Jon Chee sits down with Rabia Khan, founder and CEO of Serna Bio, to discuss her journey from Sensyne Health to building a data-driven biotech company pioneering RNA-targeted drug discovery. Rabia shares how she overcame scientific and operational hurdles, navigated contract research limitations, and boldly moved Serna Bio from the UK to San Francisco. She also reveals her intentional approach to company culture, frugality, and long-term impact—emphasizing her vision to create a biotech business built for enduring innovation, not just acquisition. Key topics covered: Breaking Industry Molds: Serna Bio puts RNA at the center, challenging protein-focused norms. Data-First Biotech: Massive RNA datasets drive unique insights. Lean Operations & Frugality: Every dollar fuels innovation. Company Building for Endurance: Built for long-term value, not quick exits. Authentic Leadership: Bold, authentic leadership for lasting impact. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Rabia Khan, at these links: LinkedIn: https://www.linkedin.com/in/rabiatkhan/ Website: https://www.serna.bio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: Principles by Ray Dalio: https://www.principles.com/ Amazon’s Six-Page Memo & Culture of Frugality: https://www.larksuite.com/en_us/blog/amazon-6-pager The Druggable Genome: https://www.nature.com/articles/nrd892 Antifragile by Nassim Nicholas Taleb: https://www.goodreads.com/book/show/13530973-antifragile Companies, Universities, & People mentioned: Serna Bio: https://www.serna.bio/ Sensyne Health: https://www.sensynehealth.com/ BenevolentAI: https://www.benevolent.com/ Y Combinator: https://www.ycombinator.com/ Bridgewater Associates: https://www.bridgewater.com/ Genentech: https://www.gene.com/ BioMarin: https://www.biomarin.com/ Regeneron: https://www.regeneron.com/ Jackie Hunter: https://www.linkedin.com/in/drjackiehunter/ Barry Ticho: https://www.linkedin.com/in/barryticho Ray Dalio: https://www.linkedin.com/in/raydalio/ Howard Marks: https://www.linkedin.com/in/howardmarksbook/ Nick Scott-Ram: https://www.linkedin.com/in/nick-scott-ram-637491b/?originalSubdomain=uk Timestamps: 00:00 Intro 02:01 Leaving Sensyne & Founding Serna Bio 03:52 The Vision: Drugging RNA with Small Molecules 09:46 Challenging the Status Quo of Protein-Centric Drug Discovery 12:30 Building the Serna Toolkit: Data, Models, and Assays 15:14 Operational Hurdles: Working with CROs & Building In-House Labs 22:03 Leadership Philosophy: Frugality, Creativity & Building Culture 28:35 Building Labs: UK vs. SF & Strategic Evolution 36:56 Vision for Serna: Building an Enduring Biotech Company 43:19 Advice to Founders: Embrace Discomfort & Authenticity 45:53 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

1
🧬 Sales Skills & Resilience: Hidden Drivers of Biotech Success | Rabia Khan (Part 3/4) 38:28

5 วันที่แล้ว38:28

38:28

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "You have to be curious. You have to enjoy the problems as opposed to view them as problems. You can view them as puzzle pieces that you get to put together, which is a lot of fun." In this episode of The Biotech Startups Podcast, Rabia Khan shares the pivotal experiences that shaped her approach to biotech innovation, from her time at BenevolentAI and Sensyne Health to building and leading high-performance teams at the intersection of biology, machine learning, and clinical data. Rabia discusses the challenges of aligning scientists and engineers around a shared language, the importance of integrating platform and program development, and the cultural shifts needed to drive real innovation in drug discovery. She also reflects on the value of curiosity, risk-taking, and the lessons learned from managing major pharma partnerships and scaling teams under intense pressure. Key topics covered: Bridging Biology & Machine Learning: Breaking barriers to spark drug discovery innovation. Platform vs. Program Development: Integrate or stagnate—unite teams to win in biotech. Building & Leading Teams: Scaling fast and thriving in high-stakes pharma. The Power of Curiosity & Risk-Taking: Question, risk, and grow—breakthroughs follow. Sales & Resilience in Biotech: Master selling and stay tough to succeed in science. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Rabia Khan, at these links: LinkedIn: https://www.linkedin.com/in/rabiatkhan/ Website: https://www.serna.bio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: ICD-10 Codes and the Classification of Disease: https://icd.who.int/browse10/2019/en HubSpot CEO on 20VC: https://podcasts.apple.com/gb/podcast/20vc-hubspot-ceo-on-where-value-accrues-in-saas-ai/id958230465?i=1000699464274 The Economist’s Approach to Business Clarity and Value Creation: https://businesslibrary.uflib.ufl.edu/economicsbooks Companies, Universities, & People mentioned: BenevolentAI: https://www.benevolent.com/ Sensyne Health: https://www.sensynehealth.com/ Serna Bio: https://www.serna.bio/ Steven Hamblin: https://www.linkedin.com/in/stevenrhamblin/?originalSubdomain=uk Kate Yen, Ph.D.: https://www.linkedin.com/in/kate-yen-448b22108/ Timestamps: 00:00 Intro 02:04 The Importance of Shared Language Across Disciplines 03:02 Platform vs. Program Development in Biotech 06:02 The Platform-Program Dichotomy and Capital Market Perspectives 07:29 Aligning Machine Learning Engineers and Biologists 09:30 Changing the Culture of Biology to Embrace Engineering Practices 11:07 The Role of Curiosity and Naivety in Innovation 12:18 Starting a Company: Risk-Taking and Support Systems 17:11 Transition from BenevolentAI to Sensyne Health 22:16 Challenges of Working with Clinical Data and ICD-10 Codes 25:17 Building and Scaling a Machine Learning Team at Sensyne Health 31:03 Leadership, Mentorship, and Hiring for Growth 33:14 The Underrated Power of Sales Skills in Biotech 36:57 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

1
🧬 Rabia Khan - Serna Bio: Bridging Science & Tech—PhDs, MBAs, & Biotech Innovation (Part 2/4) 45:29

9 วันที่แล้ว45:29

45:29

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . “I wish someone had told me when I was starting my PhD to sit down and say, ‘what do I want out of this?’ and [then] write it down. Because, unlike the UK, where PhDs are three years and time bound, in Canada, they are neither time bound nor three years. And so you can meander." In this episode of The Biotech Startups Podcast, Rabia Khan, founder and CEO of Serna Bio , joins host Jon Chee to reflect on her unconventional journey through academia, business, and biotech innovation. Rabia shares how her curiosity, resilience, and embracing uncertainty shaped her journey through a PhD in genetics and an MBA. She discusses the emotional challenges of working with animal models, the benefits and limits of business school for scientists, and personal struggles, including her father’s illness. She recounts early setbacks, like rejected consulting jobs, and how a cold email landed her at Meta (now part of Chan Zuckerberg Biohub). Rabia emphasizes “manufacturing serendipity,” differences between founder and employee mindsets, and lessons from her work at BenevolentAI, highlighting the importance of cross-disciplinary communication and challenging industry norms. Key topics covered: PhD Realities: Tackling emotional and practical research challenges Dual-Degree Insights: Balancing PhD and MBA, knowing business limits Personal Adversity: Turning family illness into resilience Career Breakthroughs: Creating and seizing biotech startup chances Bridging Disciplines: Fusing biology and ML to expand drug targets If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Rabia Khan, at these links: LinkedIn: https://www.linkedin.com/in/rabiatkhan/ Website: https://www.serna.bio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: Case in Point (book): https://caseinterview.com/case-in-point SWOT Analysis: https://en.wikipedia.org/wiki/SWOT_analysis CRISPR Technology: https://www.genome.gov/genetics-glossary/CRISPR iPSC (Induced Pluripotent Stem Cells): https://en.wikipedia.org/wiki/Induced_pluripotent_stem_cell GWAS (Genome-Wide Association Studies): https://www.nature.com/articles/s43586-021-00056-9 Ensembl: https://www.ensembl.org/index.html The concept of the “druggable genome”: https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2022.958378/full Companies, Universities, & People mentioned: Francis Crick Institute: https://www.crick.ac.uk/ BenevolentAI: https://www.benevolent.com/ Meta (Acquired by Chan Zuckerberg Biohub): https://techcrunch.com/2017/01/23/chan-zuckerberg-initiative-meta/ GSK (GlaxoSmithKline): https://www.gsk.com/ Thermo Fisher Scientific: https://www.thermofisher.com/ Sensyne Health: https://www.sensyne.com/ Sam Molyneux: https://www.linkedin.com/in/sammolyneux Amy Molyneux: https://www.linkedin.com/in/amymolyneux/ Jackie Hunter: https://www.linkedin.com/in/drjackiehunter/ Timestamps: 00:00 Intro 00:49 Rabia’s PhD Experience and Challenges 06:07 Comparing PhD Systems in Canada vs. UK 08:21 MBA Insights and Frameworks 14:28 Personal Adversity and Career Impact 17:05 Coping with Family Illness and Career Decisions 21:26 First Job at Meta and Serendipity 30:00 Postdoc at Francis Crick Institute 35:10 Joining BenevolentAI and Early Experiences 39:24 Challenges in Drug Discovery and Druggable Genome 43:41 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

1
🧬 Rabia Khan - Serna Bio: Unraveling the Genetics of AI-Driven Drug Discovery (Part 1/4) 48:30

12 วันที่แล้ว48:30

48:30

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "I was born and raised in a developing country. I was born and raised in Pakistan. And it's very interesting when you're born in a developing country. That's your world. Right? That's all you know." In this episode of The Biotech Startups Podcast, we delve into Rabia Khan's remarkable journey from her childhood in Pakistan to founding Serna Bio, an AI-enabled drug discovery company. Rabia shares how her early experiences in a developing country, her aunt's battle with schizophrenia, and the sequencing of the human genome in 2000 sparked her passion for genetics and healthcare. She recounts how her career options were either medicine or engineering, setting her on a path that would eventually lead to pioneering work at the intersection of AI and biotechnology. Rabia describes her transition to McGill University in Montreal, facing the shock of -40°C weather with only a leather jacket while navigating life as an international student with no support system. Despite these challenges, she pursued dual interests in biology and economics, finding her first research opportunity in a schizophrenia lab where she started by pipetting water and washing dishes. Key topics covered: Formative Influences: Shaped by Pakistan upbringing, aunt's schizophrenia, and genome sequencing Educational Journey: Balancing biology and economics at McGill First Research Experiences: From lab basics to discovering a disease-causing gene Decision-Making Frameworks: Applying economics principles to business decisions Family Influence: Mother's practicality and father's entrepreneurial drive guided her path If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Rabia Khan, at these links: LinkedIn: https://www.linkedin.com/in/rabiatkhan/ Website: https://www.serna.bio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: The Human Genome Project https://www.genome.gov/human-genome-project Schizophrenia https://en.wikipedia.org/wiki/Schizophrenia Opportunity Cost https://www.investopedia.com/terms/o/opportunitycost.asp Marginal Utility https://www.investopedia.com/terms/m/marginalutility.asp The Prisoner's Dilemma https://en.wikipedia.org/wiki/Prisoner%27s_dilemma Ray Dalio's Decision Making Frameworks https://www.principles.com/principles/7df5502f-46e5-47d5-8fd7-8fc70843b726/ Nassim Taleb's Antifragility https://en.wikipedia.org/wiki/Antifragile_(book) Black Swan by Nassim Taleb https://en.wikipedia.org/wiki/The_Black_Swan:_The_Impact_of_the_Highly_Improbable McGill University's Human Genetics Program https://www.mcgill.ca/humangenetics/our-programs/program-information Hydatidiform Moles Research https://www.ncbi.nlm.nih.gov/books/NBK459155/ Companies, Universities, & People mentioned: Benevolent AI: https://www.benevolent.com/ Meta: https://techcrunch.com/2017/01/23/chan-zuckerberg-initiative-meta/ Bayer: https://www.bayer.com/ BMS (Bristol Myers Squibb): https://www.bms.com/ Roche: https://www.roche.com/ Alexion: https://www.alexion.com/ Gustavo Turecki https://douglas.research.mcgill.ca/gustavo-turecki/ Rima Slim https://scholar.google.ca/citations?user=UwK8NS8AAAAJ&hl=en Danielle Malo https://www.linkedin.com/in/danielle-malo-a204a174/ Ray Dalio https://www.linkedin.com/in/raydalio/ Nassim Taleb https://en.wikipedia.org/wiki/Nassim_Nicholas_Taleb Timestamps: 00:00 Intro 03:18 Upbringing in Pakistan and Early Influences 07:27 Formative Experiences: Human Genome Sequencing and Aunt's Schizophrenia 13:49 Educational Experience: British System and Academic Rigor 17:21 Economics and Biology: Dual Interests and Decision Making Frameworks 23:31 Decision Making: Opportunity Cost and Probabilistic Thinking 28:51 International Education: Choosing McGill University 34:09 First Lab Experience: Working in a Schizophrenia Research Lab 40:43 Undergraduate Research: Discovering the Gene for Hydatidiform Moles 45:43 Father's Influence on PhD Decision 48:31 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

1
🧬Alfredo Andere - LatchBio: Revolutionizing Biopharma Data & Mastering Enterprise Sales (Part 4/4) 46:25

16 วันที่แล้ว46:25

46:25

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "Focus and commitment to niche ideas have huge payoffs." In part four of our conversation with Alfredo Andere, co-founder of LatchBio, we explore how the company evolved from a simple workflow orchestrator into a comprehensive platform serving biopharma companies and solution providers. Alfredo shares his approach to enterprise sales, emphasizing the importance of speed, focus, and building strong relationships with customers. He also delves into his philosophy on fundraising and the pivotal role of iterative development in creating impactful biotech solutions. Alfredo reflects on the challenges and rewards of working in niche markets, explaining why deep commitment and loyalty to specific problems are essential for long-term success. Whether you’re a first-time founder or an experienced entrepreneur, this episode is packed with actionable insights on building, selling, and scaling in the biotech space. Key topics covered: Iterative product development: Expanding LatchBio’s platform from workflows to data storage and analysis Biopharma vs. solution providers: How LatchBio serves these distinct customer groups Enterprise sales best practices: Qualifying leads and acting as a consultant to customer problems Fundraising strategies: Why early-stage rounds focus on vision and team, while later rounds prioritize traction The power of focus: Avoiding the trap of optionality and scaling only when ready If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Alfredo Andere, at these links: LinkedIn: https://www.linkedin.com/in/alfredoandere/ Website: https://www.linkedin.com/company/latchbio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: Viktor Frankl's "Man’s Search for Meaning": https://www.goodreads.com/book/show/4069.Man_s_Search_for_Meaning Lux Capital’s Article: Why High-Throughput Bio Research Needs Better Tools: Immediately: https://www.luxcapital.com/content/why-high-throughput-bio-research-needs-better-tools-immediately AlphaFold 2: https://alphafold.ebi.ac.uk/ Bulk RNA-seq Analysis Tools: https://en.wikipedia.org/wiki/List_of_RNA-Seq_bioinformatics_tools Paul Graham’s "How to Raise Money": https://www.paulgraham.com/fr.html Companies, Universities, & People mentioned: Latch Bio: https://latch.bio Illumina: https://illumina.com Oxford Nanopore Technologies: https://nanoporetech.com 10x Genomics: https://10xgenomics.com Fluent BioSciences: https://www.fluentbio.com/ Scale 10x: https://startupmission.kerala.gov.in/pages/scale10x Complete Genomics: https://www.completegenomics.com Kenny Workman: https://www.linkedin.com/in/kennyworkman Kyle Giffin: https://www.linkedin.com/in/kylegiffin Aidan Abdulali: https://www.linkedin.com/in/aidanabdulali Nathan Manske: https://www.linkedin.com/in/nathan-manske-0232a192/ Michael Paliotti: https://www.linkedin.com/in/michael-paliotti Timestamps: 00:00 Intro 01:56 LatchBio’s Evolution and Iterative Development 08:20 Biopharma vs. Solution Providers 14:01 Enterprise Sales Philosophy 23:38 Fundraising Strategies and Team Building 34:59 Future Vision for LatchBio 39:36 Closing Thoughts and Shoutouts 43:46 Advice to 21-Year-Old Self 46:21 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬Alfredo Andere - LatchBio: Building Biotech Data Tools to Revolutionize Life Sciences (Part 3/4) 32:14

19 วันที่แล้ว32:14

32:14

🧬The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Reduce upfront equipment costs. Accelerate R&D. Reach commercial milestones faster. 🎁TBSP listeners get exclusive offers through Excedr’s partner network—including special discounts, promos, and more: https://www.excedr.com/partners . "A lot of decisions when you're doing a startup come down to being naive enough to not know how hard it's going to be—and taking that leap of faith." In part three of our conversation with Alfredo Andere, co-founder of LatchBio, we dive into the early days of building a biotech startup from scratch. Alfredo shares how his team’s chemistry and blind faith led them to drop out of college and fully commit to solving biotech’s data infrastructure challenges. He details their rigorous market research process, which involved conducting hundreds of user interviews, and how this groundwork helped them raise an oversubscribed $5 million seed round led by Lux Capital. Alfredo also reflects on the stark contrast between cutting-edge data tools at tech giants like Google and the outdated methods still used in biotech, emphasizing the massive opportunity to revolutionize life sciences. Key topics covered: Building trust and chemistry as a founding team: The decision to drop out and go all-in on LatchBio Biotech’s data problem: Why outdated tools are holding back life sciences innovation Market research done right: 200+ pages of notes and six paying customers before launching a product Raising $5M in seed funding: How preparation and customer validation gave LatchBio a competitive edge Lessons on naivete in entrepreneurship: Why bold risks are essential for tackling big problems If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Alfredo Andere, at these links: LinkedIn: https://www.linkedin.com/in/alfredoandere/ Website: https://www.linkedin.com/company/latchbio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources and articles: Viktor Frankl's "Man’s Search for Meaning": https://www.goodreads.com/book/show/4069.Man_s_Search_for_Meaning Lux Capital Insights: https://www.luxcapital.com/riskgaming#content The Acquired Podcast featuring Jensen Huang: https://www.acquired.fm/episodes/jensen-huang Taiwan Incubator Program: https://startup.sme.gov.tw/en/ia Next Generation Sequencing (NGS): https://www.excedr.com/blog/next-generation-sequencing-101 Google and Facebook Data Infrastructure: https://medium.com/illumination/facebook-google-and-digital-public-infrastructure-ee854e1896eb Bulk RNA-seq Analysis Tools: https://en.wikipedia.org/wiki/List_of_RNA-Seq_bioinformatics_tools Machine Learning Applications in Biotech: https://cdn.fortunejournals.com/articles/ai-and-machine-learning-in-biotechnology-a-paradigm.pdf Companies, universities, & people mentioned: LatchBio: https://latch.bio/ Lux Capital: https://www.luxcapital.com Google: https://www.google.com Facebook (Meta): https://www.facebook.com Excedr: https://www.excedr.com Vivos Therapeutics: https://www.vivos.com Kenny Workman: https://www.linkedin.com/in/kennyworkman Kyle Giffin: https://www.linkedin.com/in/kylegiffin Brandon Reeves: https://www.linkedin.com/in/brandonreeves1 Jensen Huang: https://www.linkedin.com/in/jenhsunhuang/ Timestamps: 00:00 Intro 01:56 Team Chemistry and Founding Relationships 04:30 Exploring Different Project Ideas 06:34 The Decision to Drop Out of College 09:00 The Role of Naivete in Entrepreneurship 11:38 Biotech vs. Computer Science: Understanding Complex Systems 13:14 Taiwan Incubator Experience 17:22 Market Research: 200+ Pages of User Interviews 21:05 Biotech's Data Infrastructure Problem 25:21 Raising an Oversubscribed $5M Seed Round 29:38 The Future of Biotech Data Analysis 30:30 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬Alfredo Andere - LatchBio: College Friends, Biotech Beginnings & Thoughtful Persistence (Part 2/4) 34:59

23 วันที่แล้ว34:59

34:59

"You will be surprised what you can achieve with thoughtful persistence." In part two of our conversation with Alfredo Andere, co-founder of LatchBio, we dive into his transformative journey at UC Berkeley, where he developed a passion for machine learning and neuroscience. Alfredo shares how his persistence and curiosity helped him join the highly competitive Machine Learning at Berkeley club, which became a pivotal moment in shaping his entrepreneurial mindset. He reflects on the lessons learned from internships at Facebook, UCSF, and Google Brain, and how these experiences clarified his desire to pursue startup life over a traditional tech career. Alfredo also recounts the early days of working with his co-founders on ambitious projects, including their first failed startup attempt, and how those challenges led them to explore opportunities in biotech. This episode offers valuable insights into navigating uncertainty, embracing trial and error, and building meaningful collaborations. Key topics covered: The power of thoughtful persistence: How Alfredo's determination led to joining a top-tier student organization at UC Berkeley. Lessons from internships: Insights gained from working at Facebook, UCSF, and Google Brain—and why he ultimately chose startups. The importance of community: How Machine Learning at Berkeley shaped Alfredo's leadership skills and introduced him to like-minded peers. Early startup lessons: The challenges of building a product without understanding the market and the value of user research. Transitioning to biotech: How Alfredo’s passion for neuroscience evolved into tackling critical problems in life sciences with his co-founders. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Alfredo Andere, at these links: LinkedIn: https://www.linkedin.com/in/alfredoandere/ Website: https://www.linkedin.com/company/latchbio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources and articles: Machine Learning at Berkeley (ML@B): https://ml.berkeley.edu/ Viktor Frankl's "Man’s Search for Meaning": https://www.goodreads.com/book/show/4069.Man_s_Search_for_Meaning Neuralink Research Paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC6914248/ Berkeley NeuroDust Project: https://engineering.berkeley.edu/news/2016/11/neural-dust/ TensorFlow by Google Brain: https://www.tensorflow.org/ Bulk RNA-seq: https://www.scdiscoveries.com/support/what-is-bulk-rna-sequencing/ AlphaFold 2: https://alphafold.ebi.ac.uk/ Companies, universities, & people mentioned: Dyno Therapeutics: https://www.dynotx.com/ LatchBio: https://latch.bio/ Facebook (Meta): https://www.facebook.com Google Brain (now part of Google DeepMind): https://research.google/brain Neuralink: https://neuralink.com University of California, San Francisco (UCSF): https://www.ucsf.edu Kenny Workman: https://www.linkedin.com/in/kennyworkman Kyle Giffin: https://www.linkedin.com/in/kylegiffin Timestamps: 00:00 Intro 01:28 College Friendships and Early Seeds of LatchBio 03:46 Joining Machine Learning at Berkeley: Challenges and Growth 07:01 Transformational Impact of Student Organizations 12:08 Running the Machine Learning Club at Berkeley: Leadership Lessons 18:14 Introduction to Neuroscience and Life Sciences 21:38 Internships at Facebook, UCSF, and Google Brain 26:36 Lessons from Early Startup Attempts 29:12 Dropping Out of Berkeley to Pursue Entrepreneurship Full-Time 32:05 Balancing Academic and Entrepreneurial Pursuits 33:11 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬 Alfredo Andere - LatchBio: Conquering Berkeley's EECS & Building a Global Vision (Part 1) 38:20

26 วันที่แล้ว38:20

38:20

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "I had to make a decision because I knew that if nothing changed, I was just gonna fail out of EECS. I remember EECS actually sent me a letter where they were like, 'Hey, if your GPA continues this low, you will be kicked out next semester.'" In part one of our conversation with Alfredo Andere, we delve into his journey from Mexico to the prestigious EECS program at UC Berkeley. Alfredo shares his early fascination with technology, the challenges of adapting to a new educational system, and the pivotal moments that shaped his academic and personal growth. Raised in various cities across Mexico, Alfredo's passion for technology was sparked by reading biographies of tech leaders like Steve Jobs and Elon Musk. His entrepreneurial spirit emerged early when he organized a forum that attracted high-profile speakers, including former Mexican presidents, to his all-boys Catholic high school. Despite initial struggles with calculus at Berkeley, Alfredo's determination and commitment to his studies ultimately led to his success in the competitive EECS program. Key topics covered: Upbringing in Mexico: Moving between cities and experiencing different cultures Early tech inspiration: Impact of reading biographies and following Apple keynotes High school innovation: Creating a forum with 4,000 attendees and notable speakers Transition to US education: Challenges of applying to and choosing Berkeley Academic resilience: Overcoming initial struggles in EECS through intense dedication If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Alfredo Andere, at these links: LinkedIn: https://www.linkedin.com/in/alfredoandere/ Website: https://www.linkedin.com/company/latchbio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources and articles: AWS (Amazon Web Services): https://aws.amazon.com/ AstraZeneca: https://www.astrazeneca.com/ GCP (Google Cloud Platform): https://cloud.google.com/ EVO https://pmc.ncbi.nlm.nih.gov/articles/PMC6589126/ AlphaFold 2: https://alphafold.ebi.ac.uk/ Dyno Therapeutics: https://www.dynotx.com/ Bulk RNA-seq: https://www.scdiscoveries.com/support/what-is-bulk-rna-sequencing/ Companies, universities, & people mentioned: Apple: https://www.apple.com/ LatchBio: https://latch.bio/ UC Berkeley: https://www.berkeley.edu/ Uri Levine: https://il.linkedin.com/in/uri-levine Felipe Calderon: https://www.linkedin.com/in/felipe-calderon-9b104a23/?originalSubdomain=mx Vicente Fox: https://www.linkedin.com/in/vincente-fox-president/?originalSubdomain=mx Timestamps: 00:00 Intro 02:50 Alfredo's upbringing in Mexico and early influences 05:24 Reading biographies of tech leaders and early inspirations 08:09 Developing interest in technology and Apple 11:51 High school experience in Mexico 15:40 The importance of relationships in Mexican business culture 20:10 Creating a forum that attracted high-profile speakers 23:13 The power of persistence and networking 27:10 Application process to US universities and choosing Berkeley 31:22 First experiences at Berkeley and academic challenges 35:14 Struggling with calculus and the pivotal decision to commit 35:39 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬 Michael Paliotti - MilliporeSigma: Master Biotech Sales & Build High-Performance Teams (Part 4/4) 31:01

30 วันที่แล้ว31:01

31:01

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "I see myself as a player coach. I really try to do what I can to be in the trenches as much as I can. I'm out on the field." In the final part of our conversation with Michael Paliotti, we delve into his extensive experience in biotech sales and leadership. Michael shares insights on the nuances of working with different types of clients, from academia to large pharma and emerging biotech companies. He discusses his transition into management during the COVID-19 pandemic and his approach to leading and developing his team. Michael's leadership philosophy emphasizes building strong relationships, both with clients and team members. He stresses the importance of empathy, trust, and removing barriers for his team to succeed. His approach to management is rooted in his own experiences as a sales representative, allowing him to relate to his team's challenges and provide meaningful support. Key topics covered: Tailoring sales approaches for different client types: academia, large pharma, and emerging biotech Transitioning from individual contributor to team manager during the pandemic Leadership philosophy focused on relationship-building and empathy Developing and retaining talent in a competitive industry Long-term career aspirations and the importance of mentorship in biotech If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Michael Paliotti, at these links: LinkedIn: https://www.linkedin.com/in/michael-paliotti/ Website: http://www.sigmaaldrich.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Resources and articles: University of Notre Dame Biology Program: https://biology.nd.edu/undergraduate/programs-of-study/biology-major/ Duquesne University Master's Program in Biology: https://www.duq.edu/academics/colleges-and-schools/science-and-engineering/academics/departments-and-programs/biological-sciences/index.php University of Pittsburgh HIV Research Lab: https://dom.pitt.edu/id/research/clinicalresearch/hivclinicalresearch/ Kodak's Research and Development Division: https://www.kodak.com/en/company/page/innovation/ Luminex Multiplexing Equipment: https://www.rndsystems.com/products/luminex-instrumentation Companies, universities, & people mentioned: MilliporeSigma: https://www.sigmaaldrich.com/US/en University of Pittsburgh: https://www.pitt.edu/ Xerox Business Services: https://www.xerox.com/en-us/business-solutions Johnson & Johnson (J&J): https://www.jnj.com/ Novartis: https://www.novartis.com/ Pfizer: https://www.pfizer.com/ University of California, San Diego (UCSD): https://ucsd.edu/ Genoptix: https://www.genoptix.com/ Cellomics: https://www.thermofisher.com/us/en/home/life-science/cell-analysis/cellular-imaging/high-content-screening.html Nucleate: https://nucleate.xyz/ Ronald Montelaro https://www.linkedin.com/in/ronald-montelaro-49558b23/ Jane Berry https://www.linkedin.com/in/jane-berry-40038012/ Kelly Yamagata https://www.linkedin.com/in/kelly-yamagata/ Arunima Kumar https://www.linkedin.com/in/arunmaara/ Tiffany Nguyen https://www.linkedin.com/in/nguyentiffany/ Samantha Odo https://www.linkedin.com/in/samantha-odo-9a39252/ Amela Tsai https://www.linkedin.com/in/amelatsai/ Je'Anna Barrett https://www.linkedin.com/in/connectwithjeanna/ Joe Stachewicz https://www.linkedin.com/in/destinationdigital/ Frédéric Sattler https://www.linkedin.com/in/fr%C3%A9d%C3%A9ric-sattler-58a9a345/ Bernardo Jaramillo https://www.linkedin.com/in/bernardo-jaramillo-06579698/ Darae Jun https://www.linkedin.com/in/darae-jun/ Sumreet Banka https://www.linkedin.com/in/sumreet-banka-73372317/ Candice Sanscartier https://www.linkedin.com/in/candice-sanscartier/ Suzie Shrestha https://www.linkedin.com/in/suzieshrestha/ Timestamps: 00:00 Intro 02:11 Differences in working with academia, large pharma, and small biotechs 06:52 Impact of white glove service on emerging companies 09:25 The interconnected nature of the biotech ecosystem 12:26 Transitioning from individual contributor to team manager 18:09 Leadership philosophy and approach to managing a team 23:23 Long-term mindset and developing institutional knowledge 25:17 Shoutouts to supporters along the way 27:10 Advice to 21-year-old self 28:27 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬 Michael Paliotti: Blending Science, Sales, and Side Hustles in Biotech (Part 3/4) 41:59

5 weeksที่แล้ว41:59

41:59

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . “Trust takes time—but it lasts longer than any sale.” In part three of our conversation with Michael Paliotti, we dive into his transition from field application scientist to full-time sales at MilliporeSigma. He opens up about his initial hesitation, how he overcame it, and why relationship-building—not quotas—became the foundation of his sales approach. Michael reflects on the experiences that shaped his mindset, from going the extra mile for colleagues to finding interests to genuinely connect over. For him, great sales isn’t about pushing products—it’s about solving problems, building trust, and being present. He also talks about how this philosophy led to unexpected opportunities, like launching a winery with close friends during the pandemic. What started as a casual wine-tasting class turned into a business rooted in the same values that guide his sales career. An experienced team leader, Michael emphasizes coaching through effort and empathy—encouraging his reps to focus on relationships as much as results. His story is a reminder that in biotech sales, success often comes from being helpful, human, and in it for the long haul. Key topics covered : Shifting from scientist to sales and making it work Turning casual conversations into lasting trust Helping customers by going the extra mile Meeting goals without losing the human touch Coaching teams to lead with effort and empathy If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Michael Paliotti, at these links: LinkedIn: https://www.linkedin.com/in/michael-paliotti/ Website: http://www.sigmaaldrich.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources and articles: Luminex instrumentation: https://www.thermofisher.com/us/en/home/life-science/antibodies/immunoassays/procartaplex-assays-luminex/luminex-instruments.html Unreasonable Hospitality (by Will Guidara): https://www.amazon.com/Unreasonable-Hospitality-Remarkable-Giving-People/dp/0593418573 Excedr equipment leasing: https://www.excedr.com/leasing Capital Lease vs. Operating Lease: https://www.excedr.com/blog/capital-lease-vs-operating-lease Maximizing Equipment ROI: https://www.excedr.com/blog/maximizing-equipment-roi Marketing & Sales Strategies for Biotechs: https://www.excedr.com/blog/marketing-sales-strategies-for-biotechs Companies, universities, & people mentioned: MilliporeSigma: https://www.sigmaaldrich.com/US/en Charles R. Drew University of Medicine and Science: https://www.cdrewu.edu/ UC Davis Viticulture and Enology Program: https://www.ucdavis.edu/majors/viticulture-and-enology 501st Legion: https://www.501st.com/ Paso Robles AVA: https://pasowine.com/paso-robles/ava/ Pacific Wine Services: https://www.pacificwineservices.com/ Volatus Wines: https://www.volatuswine.com/ Midnight Cellars: https://www.midnightcellars.com/ Timestamps: 00:00 Intro 02:50 Getting into biotech sales and and getting interested in winemaking 04:35 Starting a winery during COVID and the story behind it 10:19 Networking in the wine industry and the power of showing up 14:14 Working at MilliporeSigma, embracing relationship-driven strategies 20:45 Building trust through informal conversations 27:47 Going the extra mile for customers and building trust through service 32:46 Transitioning from field scientist to full-time sales at MilliporeSigma 37:12 Coaching sales teams and focusing on long-term value over short-term wins 40:15 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬 Michael Paliotti: Navigating Biotech Careers & Building Lasting Relationships (Part 2/4) 43:33

5 weeksที่แล้ว43:33

43:33

"Success in this industry isn’t just about what you know—it’s about how you connect with people, bring value, and build lasting relationships." In part two of our conversation with Michael Paliotti, we delve into his journey from academic research to industry, and his eventual transition into sales within the biotech sector. Michael shares his experiences working at startups like Cellomics and larger organizations like Novartis, highlighting the pivotal moments that shaped his career path. He discusses the challenges and opportunities that came with each role, emphasizing the importance of relationships and personal branding in his success. Michael's background in both science and business, coupled with his MBA, uniquely positioned him to understand the needs of researchers and effectively communicate the value of products. His transition to a field application scientist role at Millipore, and later to a full-time sales position, showcases his ability to adapt and find his niche in the biotech industry. Michael's approach to sales, focusing on building genuine connections and becoming a trusted resource, led to his recognition as rep of the year and his reputation as an "institution" in the San Diego biotech ecosystem. Key topics covered: Transitioning from academia to roles at Cellomics and Novartis Balancing business education with a biotech career Moving from field application scientist to a full-time sales role Learning to communicate value beyond product features and build trust with customers Making bold moves, from cross-country relocation to industry shifts If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Michael Paliotti, at these links: LinkedIn: https://www.linkedin.com/in/michael-paliotti/ Website: http://www.sigmaaldrich.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: DARPA (Defense Advanced Research Projects Agency): https://www.darpa.mil/ Novartis GPR 119 diabetes research: https://pmc.ncbi.nlm.nih.gov/articles/PMC5859088/ Cal State San Marcos MBA program: https://www.aacsb.edu/accredited/c/california-state-university-san-marcos Luminex Assays: https://www.rndsystems.com/products/luminex-assays-and-high-performance-assays/discovery-assays Stanford Consortium for Regenerative Medicine: https://www.sanfordconsortium.org/ Genoptix Optophoresis Technology: https://www.bioworld.com/articles/373517-genoptix-series-b-raises-17m-to-push-laser-cell-technology?v=preview Companies & people mentioned: Cellomics: https://www.thermofisher.com/us/en/home/brands/thermo-scientific/cellomics.html Novartis: https://www.novartis.com/ Genoptix: https://genoptix.com/ EMD MilliporeSigma: https://www.emdmillipore.com/ Luminex: https://www.luminexcorp.com/ Thermo Fisher Scientific: https://www.thermofisher.com/ Pete Schultz: https://www.linkedin.com/in/peter-schultz-3254a35 Tina Nova: https://www.linkedin.com/in/tina-nova-phd-7054502 Sean Carnes: https://www.linkedin.com/in/sean-carnes-8b30b51 Cathy Schnabel: https://www.linkedin.com/in/cathy-schnabel-b657b16 Timestamps: 00:00 Intro 02:06 Michael's interest in industry and joining Cellomics 04:59 Working on DARPA grant and biosensors 07:10 Experience during 9/11 and FBI visit 10:26 Importance of product communication and marketing 14:23 Transition to Novartis and larger organization experience 18:52 Pursuing MBA while working at Novartis 22:16 Moving to field application scientist role at Millipore 25:39 Transition to full-time sales position 30:17 Building relationships and personal brand in sales 35:23 Success as a sales representative and becoming an "institution" 41:39 Reflections on career journey and finding the right niche 41:58 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬 Michael Paliotti: Navigating a Winding Path to Biotech Success (Part 1/4) 41:06

6 weeksที่แล้ว41:06

41:06

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "Growing up in a science-driven environment influenced my trajectory, from my father's chemistry background at Kodak to my own experiences in academia and research." In part one of our conversation with Michael Paliotti , Regional Sales Director at Millipore Sigma, we explore his journey from a science-driven upbringing to his early career in research and forensics. Michael shares how his father's work as an organic chemist at Kodak influenced his path into science, his academic experiences at the University of Notre Dame and Duquesne University, and his unexpected detour into optometry school before finding his true calling in research. Michael holds a degree in biology from the University of Notre Dame and a master's degree from Duquesne University. Before joining Millipore Sigma, he honed his skills in academic research at the University of Pittsburgh, forensic science with the Pennsylvania State Police, and biotech startups. Key topics covered: Growing up in a science-driven environment: The influence of Kodak and Rochester's tech industry Navigating academic uncertainty: From pre-med aspirations to finding passion in biology research Hands-on lab experience: Learning the "old-fashioned way" during graduate studies Unexpected career detours: A brief stint in optometry school and forensic science Building professional networks: The importance of mentorship and connections in career progression If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Michael Paliotti, at these links: LinkedIn: https://www.linkedin.com/in/michael-paliotti/ Website: http://www.sigmaaldrich.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: University of Notre Dame Biology Program: https://biology.nd.edu/undergraduate/programs-of-study/biology-major/ Duquesne University Master's Program in Biology: https://www.duq.edu/academics/colleges-and-schools/science-and-engineering/academics/departments-and-programs/biological-sciences/index.php University of Pittsburgh HIV Research Lab: https://dom.pitt.edu/id/research/clinicalresearch/hivclinicalresearch/ Pennsylvania State Police Forensic Science Program: https://www.upb.pitt.edu/academics/forensic-science-bs Kodak's Research and Development Division: https://www.kodak.com/en/company/page/innovation/ Companies & people mentioned: Kodak: https://www.kodak.com/en/ University of Pittsburgh: https://www.pitt.edu/ Pennsylvania State Police: https://www.pa.gov/agencies/psp.html Xerox Business Services: https://www.xerox.com/en-us/business-solutions MilliporeSigma (formerly EMD Millipore): https://www.sigmaaldrich.com/ Luminex Multiplexing Equipment: https://www.rndsystems.com/products/luminex-instrumentation Ronald Montelaro: https://www.linkedin.com/in/ronald-montelaro-49558b23/ Timestamps: 00:00 Intro 03:23 Michael's background and upbringing in Rochester, NY 07:46 Early exposure to science and the Kodak influence 11:09 University years and initial career aspirations 14:46 Unexpected detour to optometry school 17:35 Post-graduation job at Xerox Business Services 22:00 Decision to pursue a master's degree at Duquesne University 26:35 Graduate school experiences and hands-on lab work 29:03 First job as a research associate at University of Pittsburgh 31:29 Brief stint as a forensic scientist with Pennsylvania State Police 37:35 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬 Stavros Papadopoulos: Transforming Data Management (Part 4/4) 34:08

6 weeksที่แล้ว34:08

34:08

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "In life sciences, time is more important for all stakeholders. Because if you're working in life sciences, you have an obligation. You have a moral obligation to be very efficient, if not optimal." In this final part of our conversation with Stavros , founder and CEO of TileDB, we explore the challenges and opportunities in transforming data management within the life sciences sector. Stavros discusses how smaller organizations often lag behind in adopting innovative solutions due to lack of awareness and reliance on existing tools, while larger companies like big pharma are more proactive in seeking advanced technologies. Stavros highlights the importance of behavioral change in technology adoption, emphasizing that companies should focus on their core competencies rather than building infrastructure. He draws parallels with AWS, which revolutionized server management by allowing companies to focus on their products rather than infrastructure. The conversation also touches on the moral obligation of life sciences companies to optimize efficiency, given the impact on human lives. Key topics covered: Challenges for Smaller Organizations: Overcoming barriers to adopting new technologies due to limited awareness and resources. Adoption Contrast: Big pharma vs. smaller organizations in embracing innovative solutions. Behavioral Change in Technology Adoption: The need for mindset shifts in leveraging external solutions. Efficiency in Life Sciences: The moral obligation to optimize time and resources in the sector. Parallels with AWS: How outsourcing infrastructure can accelerate innovation and focus on core competencies. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Stavros Papadopoulos, at these links: LinkedIn: https://www.linkedin.com/in/stavrospap/ Website: https://www.linkedin.com/company/tiledb-inc/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Crossing the Chasm by Geoffrey Moore: http://soloway.pbworks.com/w/file/fetch/46715502/Crossing-The-Chasm.pdf Azure (Microsoft's cloud computing service): https://azure.microsoft.com/en-gb/ Companies & people mentioned: MIT: https://www.mit.edu/ TileDB: https://tiledb.com/ AWS (Amazon Web Services): https://aws.amazon.com/ Millipore Sigma: https://www.sigmaaldrich.com/ Y Combinator: https://www.ycombinator.com/ PlayStation: https://www.playstation.com/ Jake Glanville: https://www.linkedin.com/in/jacobglanville Jeff Bezos: https://x.com/jeffbezos?lang=en Timestamps: 00:00 Intro 01:10 Discussion on working with smaller companies and scalable products 02:16 Stavros explains how TileDB can replace solution architects 05:07 Discussion on freeing up resources for high ROI initiatives 06:22 Stavros highlights the difficulty of behavioral changes in adopting new technologies 10:16 Jon reflects on the importance of valuing time in life sciences 12:57 Introduction of TileDB's new product, Carrara 18:16 Discussion on meeting users where they are with Carrara 20:06 Stavros shares his vision for TileDB's future adoption 23:30 Jon expresses enthusiasm for TileDB's impact on health outcomes 26:15 Shoutouts to supporters and team members 29:32 Advice to his 21-year-old self 30:30 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬 Stavros Papadopoulos: Scaling TileDB & Revolutionizing Data Infrastructure (Part 3/4) 36:00

7 weeksที่แล้ว36:00

36:00

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "We're wasting money. You're wasting money as an organization, like, hundreds of millions of dollars that can save you that money easily. But you have to start reasoning a little bit differently." In this third part of our conversation with Stavros Papadopoulos , founder and CEO of TileDB, we delve into the company's ambitious vision to revolutionize data management in the life sciences sector. Stavros shares the journey of TileDB from its inception as a highly technical solution to its current position as a potential game-changer in how organizations handle diverse data types. He discusses the challenges of selling innovative solutions to large pharmaceutical companies and the stark contrast in adoption between big pharma and smaller organizations. Stavros, with his background as a technologist from MIT, details the early days of TileDB, emphasizing the intense focus on technological innovation and performance optimization. He describes the company's evolution from a small team of highly skilled engineers to securing significant funding and attracting major customers in the life sciences sector. Throughout the conversation, Stavros highlights the philosophical aspect of TileDB's mission, stressing its potential impact on accelerating scientific discovery and ultimately saving lives. Key topics covered: TileDB's Vision for a Multimodal Database: Replacing fragmented data management systems Challenges in Selling Innovative Solutions: Large pharmaceutical companies as a target market The Contrast Between Big Pharma & Smaller Organizations: Adopting new technologies The Philosophical Drive Behind TileDB's Mission: Accelerating scientific discovery Organizational Inertia & Decision-Making Complexities: Enterprise software adoption If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Stavros Papadopoulos, at these links: LinkedIn: https://www.linkedin.com/in/stavrospap/ Website: https://www.linkedin.com/company/tiledb-inc/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Crossing the Chasm by Geoffrey Moore: http://soloway.pbworks.com/w/file/fetch/46715502/Crossing-The-Chasm.pdf Intel's Parallel Computing Lab: https://faculty.cc.gatech.edu/~echow/ipcc/ Intel Science and Technology Center for Big Data at MIT CSAIL: http://hammer.csail.mit.edu/ Hong Kong University of Science and Technology: https://hkust.edu.hk/ AWS (Amazon Web Services): https://aws.amazon.com/ Azure (Microsoft's cloud computing service): https://azure.microsoft.com/en-gb/ Companies & people mentioned: Intel: https://www.intel.com/ MIT: https://www.mit.edu/ TileDB: https://tiledb.com/ Broad Institute: https://www.broadinstitute.org/ Silicon Valley Bank: https://www.svb.com/ Browne Consulting: https://browneconsulting.com/ Snowflake: https://www.snowflake.com/ Databricks: https://www.databricks.com/ Seth Shelnutt: https://www.linkedin.com/in/seth-shelnutt/ Dimitris Papadias: https://cse.hkust.edu.hk/admin/people/faculty/profile/dimitris Yufei Tao: https://www.linkedin.com/in/yufei-tao-328b0b251/?originalSubdomain=hk Timestamps: 00:00 Intro 01:18 Early days of TileDB and its mission 06:36 Building a high-performance team and securing early customers 09:22 Discussing the vision behind TileDB 12:11 The problem of data infrastructure complexity 16:26 TileDB as a multimodal database for discovery 19:27 The inefficiency of in-house database solutions in pharmaceuticals 23:09 Overcoming organizational inertia in adopting new technologies 28:20 The necessity of TileDB for drug discovery 29:48 Differences in working with smaller vs. larger organizations 33:21 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

The Biotech Startups Podcast

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🧬Stavros Papadopoulos: How Serendipity Sparked TileDB's Startup Journey (Part 2/4) 42:22

7 weeksที่แล้ว42:22

42:22

🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "Serendipity plays a big role, but you need to chase it, man. You need to [chase it] and you need to perform. You need to deliver [on] your end of the deal." In part two of our conversation with Stavros Papadopoulos , founder of TileDB, we delve into his journey from academia to entrepreneurship. Stavros shares his experiences at MIT and Intel, and the serendipitous events that led to the founding of his company. He details the transition from working on cutting-edge database systems to identifying a market need in the life sciences sector, particularly in handling complex genomic data. Stavros's background in computer science and his work at the intersection of Intel and MIT uniquely positioned him to tackle the challenges of building a new type of database system. His journey highlights the importance of proactivity, networking, and being prepared for unexpected opportunities. He also shares valuable insights on the realities of starting a database company, including the significant funding requirements and the necessity of continuous learning. Key topics covered: Transition from academia to entrepreneurship: Seizing opportunities at MIT and Intel Developing TileDB: C reating a novel database system for complex data types Fundraising journey: From angel investors to venture capital Challenges of starting a database company: High costs and talent requirements Importance of mentorship and building win-win relationships in tech entrepreneurship: Key strategies for success If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Stavros Papadopoulos, at these links: LinkedIn: https://www.linkedin.com/in/stavrospap/ Website: https://www.linkedin.com/company/tiledb-inc/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Mentions: Resources & Articles: Disciplined Entrepreneurship: 24 Steps to a Successful Startup by Bill Aulet: https://www.d-eship.com/ Zero to IPO by Frederic Kerrest: https://www.linkedin.com/pulse/book-day-zero-ipo-frederic-kerrest-summary-mircea-ioan-soit-kvspe/ TileDB database technology: https://cloud.tiledb.com/academy/what-is-tiledb/ Genomics DB (precursor to TileDB): https://www.tiledb.com/blog/population-genomics-data-with-tiledb MIT Technology Licensing Office: https://tlo.mit.edu/ Broad Institute's VCF (Variant Call Format): https://www.broadinstitute.org/publications/broad12186 Rady Children's Institute for Genomic Medicine (RCIGM): https://radygenomics.org/begin-ngs-newborn-sequencing/ UK Biobank: https://www.ukbiobank.ac.uk/ Companies & People: Intel: https://www.intel.com/ MIT: https://www.mit.edu/ TileDB: https://tiledb.com/ Broad Institute: https://www.broadinstitute.org/ Nexus Venture Partners: https://nexusvp.com/ Sam Madden: https://www.linkedin.com/in/samuel-madden-8ba0835/ Frederic Kerrest: https://www.linkedin.com/in/fkerrest/ Timestamps: 00:00 Intro 01:24 Transitioning from Hong Kong to MIT/Intel 11:30 The importance of proactivity and hustle in seizing opportunities 20:59 Working on database systems at MIT/Intel 29:08 The serendipitous encounter that led to starting TileDB 32:16 Developing TileDB: A database for non-tabular data and machine learning 35:30 Solving scalability issues for the Broad Institute 36:55 Raising initial funding and spinning out TileDB from MIT/Intel 37:26 Challenges of starting a database business 38:15 Structuring TileDB's launch as a win-win for all stakeholders 39:47 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…

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The Biotech Startups Podcast « » 🧬 Mark Kotter - bit.bio - Part 2 | Navigating Between the Clinical & Research Worlds | Lessons in Combining Different Fields | The Evolution of Cell Therapies | Transitioning from Academia to Entrepreneurship

🧬 Mark Kotter - bit.bio - Part 2 | Navigating Between the Clinical & Research Worlds | Lessons in Combining Different Fields | The Evolution of Cell Therapies | Transitioning from Academia to Entrepreneurship

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The Biotech Startups Podcast « »
🧬 Mark Kotter - bit.bio - Part 2 | Navigating Between the Clinical & Research Worlds | Lessons in Combining Different Fields | The Evolution of Cell Therapies | Transitioning from Academia to Entrepreneurship