119: Bio-Reactor or Bio-Rocket? Scaling Up with Arsenale Bio's Massimo Portincaso

Grow Everything Biotech Podcast

Karl and Erum sit down with Massimo Portincaso, founder of Arsenale BioYards, to discuss the urgent need to rethink how we scale biomanufacturing. Massimo shares why today’s approach to industrial biotech—modeled after biopharma—is fundamentally flawed and how Arsenale is flipping the script. From nature co-design to AI-driven strain selection, he lays out a bold vision for scaling bio-based production in a way that is economically viable and industrially scalable. If you care about the future of precision fermentation, sustainable materials, and the bioeconomy, this is a conversation you don’t want to miss!

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Links and Resources:

• Arsenale Bioyards

• Farm.One

• Common Side Effects (TV series)

• Nature Co-Design report

• Genomatica aka Geno

• Officinae Bio (now Maravai Life Sciences)

• "Scaling Cells, Dreaming Big: The Biomanufacturing Cloud with Synonym’s Edward Shenderovich"

Topics Covered:

Biomanufacturing, bioreactors, downstream processing, upstream processing, bioengineering, bioeconomy, italian biotech

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Music by: Nihilore

Production by: Amplafy Media