The following are Biology related podcasts for educational purposes.
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With the convergence of data, computing power, and new methods, computational biology is at its most exciting moment. At PSI, we're asking the leading researchers in the field to discover where we're headed for, and which exciting pathways will take us there. Whether you're just thinking of starting your research career or have been computing stuff for decades, come and join the conversation!
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Clarivate Conversations in Healthcare is a collection of candid interviews with key leaders and experts. Veteran industry journalist Mike Ward explores business challenges and opportunities the industry currently faces, including COVID-19, clinical innovation, deal making, emerging market dynamics, data and technology, new engagement models, patient centricity and much more. Hosted on Acast. See acast.com/privacy for more information.
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Episode 19 - Alex MacKerell: Simple physics, missing experimental data, and model compatibility
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Send us a text In episode 19, Alex and I discuss the history and future of developments in the CHARMM family of force fields, and whether Alex believes there is more physics that we need to include in our classical energy functions to work around our current challenges in biomolecular modeling. Throughout the conversation, he's advocated for a prag…
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Episode 18 - Erik Lindahl: Finding simple and novel ideas, starting an experimental lab, and ligand-gated ion channels
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Send us a text In Episode 18, Erik Lindahl reminds us that despite our dependence on computational power and advanced technology, real breakthroughs are often waiting for those who have the patience to think carefully, come up with eye-opening ideas, and follow their sense of purpose. We discuss the different ways to be smart in science, highlighti…
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Episode 17 - Caroline Lynn Kamerlin: Deep interdisciplinarity, enzyme promiscuity, and science in society
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Send us a text In episode seventeen, Caroline Lynn Kamerlin talks about the art of asking bold and impactful scientific questions, as well as how to engage in truly interdisciplinary research, something she sees as a consequence of her formal background in natural philosophy. We talk about the emerging concepts around enzyme promiscuity, how this v…
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Episode 16½ - End-of-season 2 commentary
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Send us a textโดย Miłosz Wieczór
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Episode 16 - Janusz Bujnicki: Structural modeling, RNA modifications, and advising policy-makers on science
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Send us a text In the sixteenth episode, Janusz Bujnicki tells me about his early switch to bioinformatics, a stroke of serendipity that defined his future career, and how he later managed to reincorporate both biophysics and experimental biology into his research agenda. We talk about the current state of the field of RNA structural prediction, an…
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Episode 15 - Paulo CT Souza: Developing a universal coarse-grained force field, and approaching the science of molecular complexity
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Send us a text In the fifteenth episode, Paulo Souza and I discuss the challenges inherent in managing a project of such a scope, and the philosophy behind the systematic way in which Martini is continuously improved and reparameterized. Paulo describes how a user-centric approach helps refine and troubleshoot the model through its widescale adopti…
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Episode 14 - Syma Khalid: New ways to fight bacteria, the bacterial envelope, and kindness & openness in academia
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Send us a text In the fourteenth episode, Syma Khalid and I talk about the challenges we're faced with when trying to understand the environment of the bacterial cell envelope, and the outer membrane in particular. We discuss how the lessons taken from the computational study of these structures can inform the design of future antibacterial agents.…
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Episode 13 - Daniel Zuckerman: Trajectory ensembles, writing books, and learning biology through physics
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Send us a text In the thirteenth episode, Daniel Zuckerman and I talk about textbooks on statistical biophysics and a physics-based vision of biology, a few of which he himself authored. Daniel reveals that his passion for clarity in writing comes from his early humanities background, and makes a case for how well-thought and physically motivated n…
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Episode 12 - Vlad Cojocaru: Simulating transcriptional regulation, returning to our home countries, and the scales of the genome
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Send us a text In the twelfth episode, Vlad Cojocaru and I discuss how the simulation field can integrate further layers of complexity in modeling transcription control and genome organization in humans. Vlad shares his insights on the computational biology of transcription factors, including DNA-mediated allostery and pioneer transcription factors…
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Episode 11 - Justin Lemkul: Providing technical help online, sharing expertise, and polarization in nucleic acids
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Send us a text In the eleventh episode, Justin Lemkul and I talk about the motivations and challenges behind providing technical help on online forums and mailing lists. Justin shares his story of becoming a prolific technical advisor for the Gromacs community, which evolves into a discussion about automatability, the role of expertise in running a…
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Episode 10 - Ariane Nunes-Alves: Kinetics in drug design, molecular crowding, and the social life of a PI
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Send us a text In the tenth episode, Ariane Nunes-Alves and I talk about a kinetics-centric view of drug design, making the case that modeling kinetics in atomistic simulation is an important frontier that, despite clear biomedical relevance, is rarely explicitly addressed either in model parameterization or with the latest AI methods. We discuss t…
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Episode 9 - Michele Vendruscolo: Preventing protein misfolding, fostering public engagement of scientists, and AI tools in drug design
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Send us a text In the ninth episode, Michele Vendruscolo and I discuss the current state of research on misfolding diseases, typically associated with excessive protein aggregation and formation of insoluble amyloids. Michele presents an optimistic perspective in which the convergence of recent clinical and software developments opens up new avenue…
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Episode 8½ - My commentary: Wrapping up the first season
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Send us a text In this episode, I'm attempting to string together the most common threads brought up by my guests in the first eight interviews on the podcast. Reflecting on these conversations, I'm suggesting some grand challenges for the field in the years to come.โดย Miłosz Wieczór
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Episode 8 - Rossen Apostolov: Managing scientific collaboration, the biggest project of European biophysics, and seeding schools of thought
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Send us a text In the eight episode, Rossen Apostolov and I depart from the standard format to talk about the core concepts behind BioExcel, the European Center of Excellence for computational biology. We discuss their main objectives and challenges, from working with code to organizing schools and webinars, talk about the challenges of sustaining …
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Episode 7 - Aleksei Aksimentiev: Nanobiotechnology, the importance of mentoring, and engineering serendipity
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Send us a text In the seventh episode, Aleksei Aksimentiev and I delve into the intersection of physics, biology, and nanotechnology, exploring the innovative world of nanopores and biomolecular sequencing. Aleksei shares his journey from particle physics in Ukraine to leading-edge research in the US, and underscores how on the unpredictable path o…
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Episode 6 - Giulia Palermo: Reimagining scientific creativity, the RNA revolution, and truly multiscale systems
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Send us a text In the sixth episode, Giulia Palermo and I discuss the challenges of studying truly multiscale biomolecular systems, such as the CRISPR/Cas9 complex she famously got involved with. While such problems can take us way out of our comfort zones, they also provide us with clear pathways to innovative and transformative science, something…
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Episode 5 - Paul Robustelli: The dissolving barrier between industry and academia, embracing our artistic side, and new models of funding
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Send us a text In the fifth episode, Paul Robustelli and I discuss how the once very sharp boundary between academia and industry has been becoming increasingly porous, and what implications it will have for future careers in science. Paul shares his experiences and observations about the competing models of funding scientific research, and makes a…
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Episode 4 - Modesto Orozco: Computations driving experiments, opening simulation data, and integrating knowledge across sources and scales
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Send us a text In the fourth episode, Modesto Orozco and I talk about the rough path to the predictive power modern computational science has achieved in biology, and the immense possibilities it opens to today's computational biologists working across the scales of space and time. Modesto also reflects on why sharing simulation data is crucial to …
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Episode 3 - Wojtek Kopeć: Science as a social endeavor, learning from industry, and the experience of starting a new lab
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Send us a text In the third episode, Wojtek Kopeć and I discuss the overlooked yet exciting social aspect of scientific collaboration, and what the world of academia could learn from the industry and statisticians to avoid falling behind. Wojtek also shares his personal experience of starting a lab as a new PI, and we reflect on the role of honesty…
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Episode 2 - Max Bonomi: Interoperability, AI-generated ensembles, and recognizing all contributions to science
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Send us a text In the second episode, Max Bonomi and I discuss efforts to achieve interoperability and portability in the computational community, and how the AI structural revolution will unfold to bring us realistic molecular ensembles. We then move on to ask how the entire range of contributions to science can be recognized, particularly at the …
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Episode 1 - Pilar Cossio: Modeling experimental setups, overpublishing, and maintaining code
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Send us a text In the first episode, Pilar Cossio and I discuss the radical progress in integrating simulations with experiments, and the excitement about recent progress in modeling cryo-EM tomography data. We share thoughts on the sustainability of our publishing practices, and comment on the challenges of funding the maintenance of scientific co…
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Send us a text What is this all about? Does the computational community need a podcast? Along with the first interview, I'm sharing the idea behind PSI, and explaining why the time is ripe for a new marketplace of ideas to drive the changes in how we do science. Everyone is invited, from ambitious undergraduates to seasoned veterans!…
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Lighting the touch paper for next generation nucleic acid therapies
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In this episode Mike Ward, Clarivate’s Head of Thought Leadership for Life sciences and healthcare, spoke to Johnny Ohlson, Founder of Touchlight, a company who has developed a novel synthetic DNA vector. In recent years, we've seen that by harnessing the power of DNA, it has been possible to achieve success in treating previously incurable heredit…
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Realizing the patient-friendly future of clinical trials
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In this episode of Conversations in Healthcare, Ergomed founder Dr. Miroslav Reljanović talks to Mike Ward about how the COVID-19 pandemic has nudged clinical trials towards greater efficiency and inclusivity – and what’s needed to make good on this promising trend. Hosted on Acast. See acast.com/privacy for more information.…
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How Patient Connect addresses unmet needs at the point of care
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In this episode of Conversations in Healthcare, Mike Ward speaks with Dr. Grace Lomax, Clinical Director at Patient Connect, a part of Clarivate. Grace’s experience as a physician highlighted numerous unmet needs beyond just clinical issues – especially around healthcare literacy, education at the point of care, adherence and more. She discusses ho…
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Social determinants: barriers to healthcare impacting racial and ethnic minorities
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In this episode of Conversations in Healthcare, Matthew Arnold, Principal Analyst at Clarivate speaks with Dr. Kenton Johnston, Associate Professor of Health Management and Policy at Saint Louis University about disparities in the US health system. Matthew and Ken discuss both the historical context as well as the evolution of the system since the …
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How Novo Ventures prioritized their investment strategy during the pandemic
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In this episode of Conversations in Healthcare, Mike Ward speaks with Naveed Saddiqi, Senior Partner at Novo Ventures, one of the largest venture capital groups in the life sciences sector. Naveed shares about the firm’s mandate to generate funds for the Novo Nordisk Foundation, how the pandemic impacted their investment strategy and what excites h…
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How Healx uses AI to transform rare disease drug discovery
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In this episode of Conversations in Healthcare, Mike Ward speaks with Dr. Tim Guilliams, the co-founder and CEO of Healx. Healx is an artificial intelligence-powered technology company that's dedicated to helping rare disease patients access life improving treatments. Mike and Tim discuss the company’s innovative approach to drug discovery, choosin…
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How the pandemic shifted Roche’s priorities and R&D investments
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In this episode of Conversations in Healthcare, Mike Ward speaks with Richard Erwin, general manager and managing director of Roche Products Limited (UK), which was recorded in collaboration with One Nucleus's ON Helix conference (June 2021). Richard shares how the pandemic has shifted Roche’s priorities and why the organization has heavily increas…
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Optimizing patient-first clinical trials with advanced site intelligence
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In this episode of Conversations in Healthcare, Mike Ward speaks with Oriol Serra, former Head of Site Intelligence and Selection at Pfizer and Simon Andrews, Vice President of RWD Engagements and Innovations at Clarivate about optimizing patient-first clinical trial design and ensuring trial groups align to real-life populations and needs. The gro…
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Showing the value of regulatory intelligence in pharma
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In this episode of Conversations in Healthcare, Mike Ward speaks with Carolyn Hynes, Director of Regulatory Intelligence at AstraZeneca, and Céline Rodier, Senior Health Policy Manager at Clarivate, about strategies and tools to gather and assess regulatory intelligence, as well as KPIs and approaches to demonstrating ROI within your organization. …
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Overcoming health inequity in the U.S. and the role of telehealth: Ideas and best practices from Cigna, Henry Ford Health System and the eHealth Initiative
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Increased reliance on telehealth services has been one of the most significant care delivery shifts prompted by the COVID-19 pandemic. However, the pandemic has also thrown more light on the challenges of health inequity in the United States, especially among African American and Hispanic communities. We discuss these issues and potential solutions…
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Best practices for university - healthcare partnerships: Learnings from the Institute of Cancer Research
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In this episode of Conversations in Healthcare, Mike Ward, Head of Thought Leadership, Life Sciences and Healthcare at Clarivate, speaks with Dr. Toby Richardson, who is Head of Business Development and Licensing; Deputy Director of Business and Innovation at The Institute of Cancer Research. Mike and Toby discuss how research collaborations betwee…
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Best practices for university – healthcare partnerships: Learnings from Oxford
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In this episode of Conversations in Healthcare, Mike Ward, Head of Thought Leadership, Life Sciences and Healthcare at Clarivate, speaks with Dr. Phil Clare, the Deputy Director, Research Services (Knowledge Exchange and Engagement) at the University of Oxford. Mike and Dr. Clare discuss the key role that university research plays in shaping new me…
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The evolution of the asset-centric approach in biotech venture capital
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In this episode of Conversations in Healthcare, Mike Ward, Head of Thought Leadership, Life Sciences and Healthcare at Clarivate, speaks with Francesco De Rubertis, a co-founder and managing partner at Medicxi, one of the most prominent financial supporters of innovative biotech activity. Francesco provides insights into how the biotech venture cap…
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Clarivate market experts break down the opportunities and potential threats for 2021’s Drugs to Watch – the key drugs expected to be blockbusters by 2026. Hosted on Acast. See acast.com/privacy for more information.
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Pivoting a product launch during the pandemic
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In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Bryan Witherbee, President & CEO of Adarza BioSystems. Earlier this year, Adarza raised 25 million dollars to support the full commercialization of Ziva, an automated biological platform which delivers comprehensive, h…
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The past, present and future of next generation sequencing
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In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG talks to Nick McCooke, CEO of Longas Technologies. Having been at the forefront of developing next generation sequencing, Nick talks to Mike about his past work, current projects and future predictions for this key technology in …
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COVID-19, multi-stem clinical trials and a new way of fundraising
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In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership talks to Gil Van Bokkelen, founder, chairman and CEO of Athersys Inc. They discuss the company’s clinical program that is focusing on a special class of stem cells which display very unique properties and have been obtained from healthy young consenting don…
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Early planning key to successful access and product launch
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In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, speaks with Alison Kneen, Senior Vice President, Global Market Access and Head of the Centre of Innovation and Regulatory Science (CIRS) and DRG Abacus. Learn why early and thorough planning is so important for a successful product launch, and how A…
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Transforming the treatment of cancer with oncolytic viruses
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In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, speaks with Stephen Russell, CEO of Vyriad. Dr. Russell reveals invaluable insights for those looking for or currently putting together partnership deals. Stephen shares his journey from academia at the Mayo Clinic to founding Vyriad, and eventually…
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Possible treatment for COVID-19 related respiratory failure
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In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Jonathan Javitt, CEO of NeuroRx. Dr Javitt discusses how NeuroRx is working in collaboration with Relief Therapeutics on Aviptadil, a synthetic version of vasoactive intestinal peptide, and a potential treatment of COV…
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Utilizing pluripotent stem cells in cell therapy
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In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Brian Culley, CEO of Lineage Cell Therapeutics. Brian and Mike discuss the company’s cell therapy program, utilizing pluripotent stem cells, initially targeting dry age-related macular degeneration, acute spinal cord i…
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How Glympse Bio oversubscribed their Series B funding amidst the pandemic
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In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Dr. Caroline Loew, President and CEO from Glympse Bio. They discuss the biotech’s focus on both disease detection and response to treatment using bioengineered sensors, starting with NASH. Dr. Loew also shares career a…
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A novel approach to treating neurodegenerative disease
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26:19
In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Dr. Leen Kawas, president and CEO of Athira Pharma. Dr. Kawas shares the company’s innovative approach to treating Alzheimer’s disease by developing small molecules to restore neuronal health and stop neurodegeneration…
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1
An update from biopharma’s hotspot
27:26
27:26
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27:26
In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, Part of Clarivate talks to Bob Coughlin, president and CEO of the Massachusetts Biotechnology Council. Bob provides insights from what is unarguably the world’s number one biopharma hotspot. Bob and Mike discuss how the industry…
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1
Addressing strategic challenges for biotech companies
30:55
30:55
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30:55
In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, talks to Dr Srikanth Rajagopal (or Doc, as he is fondly referred to). Doc, a partner at DRG Consulting, whose areas of expertise include product and portfolio strategy to name a few, chatted to us about common strategic challenges biotechnology comp…
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1
Collaborating with officials to continue developments
39:08
39:08
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39:08
In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG talks to Joe Panetta, President and CEO of BIOCOM. Joe talks around how BIOCOM has worked closely with government officials to ensure the life science community can continue to function throughout the COVID-19 pandemic, and how t…
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1
How including patients can help with the fight against Parkinson’s Disease
21:27
21:27
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21:27
In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG talks to Charlotte Allen and Russ Bradford from Parkinson’s Concierge. Russ and Charlotte offer a unique insight into how being a patient centric organisation enables them to help the Parkinson’s Disease community improve their q…
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1
Maximising R+D efforts through better epidemiology understanding
23:13
23:13
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23:13
In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, talks to Mike Hughes, Senior Director of Epidemiology at DRG. With epidemiology entering our daily vernacular, thanks to the Covid-19 pandemic, Mike gives a definition of what it is, the approaches used to model epidemiology ass…
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