How python hearts grow and shrink

PNAS Science Sessions

How python hearts grow and shrink

Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us.

In this episode, Leslie Leinwand, of the University of Colorado in Boulder, and Claudia Crocini, of Charité – Berlin University of Medicine in Germany, describe how the hearts of constricting pythons change size after meals.

In this episode, we cover: •[00:00] Introduction •[01:19] What is the natural context for cardiac hypertrophy in constricting pythons? •[02:48] What were the mechanisms involved in this process that you identified? •[05:27] What did you discover about the mechanisms of heart size regression in these snakes? •[07:24] What are the next steps in this line of research? •[08:21] Conclusion.

About Our Guest: Leslie Leinwand Professor University of Colorado

Claudia Crocini Junior Research Group Leader Charité – Berlin University Medicine

View related content here: https://www.pnas.org/doi/full/10.1073/pnas.2322726121

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