Health Discourse with Sakshi & Sushant- Episode 12

Genefitletics

It has been found that 33% of adult female population suffer from depression, while 1 in 5 men would have this growing mental health issue. Stress is rampant while millions of people deal with dementia & Parkinson's. While there are solution such as drugs & antidepressants to manage these growing mental health conditions, we have not seen any application of science to carve out preventive solution for growing mental health issues. We all know the role of gut microbiome in our brain health via the gut-brain axis. Gut microbes not only produce neurotransmitters but also secrete certain toxic metabolites which could travel to brain & trigger inflammation. But research has now found that the second largest coloniser of microbes in the body- mouth has a vital role to play not only in our oral health but a range of systemic health issues such as type 2 diabetes, heart diseases, arthritis, IBD, colon cancer & more. Improper nutrition & bad oral hygiene could lead to trigger oral microbial dysbiosis which over activates immune response & leads to chronic inflammation. This prolonged inflammation creates a situation of leaky gum which allows certain oral microbes such as streptococcus mutans & P Ginagavalis translocate from mouth into bloodstream & brain where it could secrete toxin metabolites & directly trigger onset & progression of brain health issues such as dementia. Specifically P. Gingivalis could secrete neurotoxic protease-Gingipain which could lead to creation of Amyloid Beta Protein Plague which is associated with dementia. It has also been found that people suffering from Chronic Periodontal disease & also experience neuro inflammation. Besides, Oral microbial dysbiosis is also connected with loss of dopamine production neurons, the hallmark of motor dysfunction & parkinsons disease. Our today’s talk opens pandorabox on oral microbiome- brain health connection. We are the only company in India that analyses oral microbiome functions to translate early pre-disease signals into unique molecular insights & carve our precision nutrition interventions to bring back your body back into homeostasis. More details here :https://genefitletics.com/orahyg/