Perinatal Pharmacokinetics and Serum Methadone/Metabolite Ratios

Addiction Medicine: Beyond the Abstract

In episode nine of Addiction Medicine: Beyond the Abstract, we are joined by Dr. John McCarthy, an associate professor of psychiatry and volunteer clinical faculty at the University of California Davis. In his recent study, Dr. McCarthy and his colleagues examined the significance of serum methadone/metabolite ratios (or MMRs). In particular, they looked at the changes in these ratios for the expecting mother throughout pregnancy and sought to use these ratios to objectively guide methadone dosing.

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