The immune system is extremely vital for the proper functioning of our body, and important as it is, it also remains somewhat of an enigma to many of us, scientists included. With this podcast, I try to throw some light on this topic, though I must say I’m no expert authority on it, in fact quite far from it, I’m just as clueless as anyone else.
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Hello everyone. I’m a doctor, currently pursuing my MD in human physiology. In this podcast, I try to explain the workings of the human body in an entertaining, digestible fashion.
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Autophagy is the process in which cells degrade and recycle their own components. While usually occurring in nutrient starvation, autophagy is also crucial for various other physiological and pathological processes. To reach out to me email me at thephysiologybeat@gmail.com
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A kind of programmed cell death, apoptosis is very vital for normal functioning of the body.
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It is a type of endocytosis by which cells, especially phagocytes, digest substances, usually bacteria and other pathogens. Things that I forgot to mention: 1. The process by which apoptotic cell debris are digested is specifically called efferocytosis, 2. The size of substances undergoing phagocytosis is more than 0.5 micron.…
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Transport Across the Cell Membrane
24:16
24:16
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24:16
For cells to function well, substances have to pass across the cell membrane, which occurs passively or actively or by using vesicles.
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A deep dive into the extracellular matrix, which not just fills up the space between cells but performs a wide variety of functions.
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Cell adhesion molecules (CAMs) link cells to one another. Overall, they are of four types - cadherins, integrins, selectins and immunoglobulin superfamily - and perform a wide range of functions.
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They are connections between adjacent cells, that regulate coordination between the cells and tissues.
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The cytoskeleton helps the cell move and adapt to external signals. It includes actin filaments, microtubules and intermediate filaments.
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The Golgi apparatus mainly processes and sorts the various proteins formed in the cell.
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Ribosomes are the protein machinery of the cell. Made up of two subunits, they synthesise proteins in a three step process - initiation, elongation and termination.
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A brief overview of the endoplasmic reticulum, organelles which take part in initial protein synthesis.
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Wishing everyone a very happy New Year. In this episode, I briefly talk about the lysosome, a cell organelle that primarily takes part in degradation of waste products and harmful pathogens.
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Popularly known as the powerhouses of the cell, mitochondria are indeed important. Without them, we wouldn’t last.
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The nucleus is a very important component of the cell. It contains all our genetic information, though which it controls almost all aspects of our biology.
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In this episode, I explain in detail about the structure of the cell membrane, a component essential to all cells.
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Cells are the building blocks of not just our human bodies but all life. Understanding them is fundamental to understanding ourselves.
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Life is constant improvement, they say. So, why not better my podcast, right? Starting from now, I’ll cover topics in an orderly and consistent fashion. Stay tuned.
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Quite popular among people wanting to lose weight, the ketogenic or keto diet is indeed beneficial albeit a few possible side effects.
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A balanced diet, as we all know, is highly important for our good health. In this episode, I talk about what makes a healthy diet. Also, I’ve made my first video for YouTube. https://youtu.be/dzhPyzvJPOQ Check it out please.
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Assessment of the arterial pulse is commonly done during physical examination. It gives us vital clues about the health and disease of the body. In this episode, I give a overview of the pulse examination.
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Sharing a bit of what I know about Parkinson’s disease.
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Respiration in high altitudes
11:41
11:41
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11:41
Breathing in high elevations is a challenge to our body. In this episode, I talk about the mechanisms carried out by the body to adapt to high altitudes and also the conditions in relation to them.
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Salivary secretions play a very vital role in protecting our mouth from various pathogens and also helping digest the food to some extent. In this episode, I talk about how saliva is produced, it’s functions and diseases relating to it.
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Overview of the Gastrointestinal System
16:25
16:25
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The gastrointestinal system or GIT is very integral to our proper body function and mainly performs the functions of taking in, digesting and absorbing the nutrients. To keep the GIT running, a lot of regulatory actions need to be carefully coordinated by our body.
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Transport of carbon dioxide in the body
16:42
16:42
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Carbon dioxide is a waste product in our body. In this episode, I talk about how it is carried in the blood and then exhaled through the lungs.
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Oxygen transport in the body
17:41
17:41
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17:41
Oxygen is a vital requirement for our body. All our cells need it to carry out their functions. But, how does that oxygen reach the tissues? That’s what I talk about in this episode.
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Pathogenesis of diabetes mellitus
23:42
23:42
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23:42
Diabetes mellitus is one of the most worrisome diseases of our times. In this episode, I talk about its various subtypes and what leads to their development.
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Sodium-Potassium-ATPase Pump
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12:01
A very important component of our cell membranes, the Na-K-ATPase pump carries out several important functions in our body.
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In this episode, I briefly go through the tests with which we can assess the functioning of the lungs.
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In this episode, I talk about the other tests except bilirubin that we can do to assess the condition of the liver.
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Bilirubin is a very important test to assess liver function. In this episode, I talk about how it’s formed, metabolised and the different causes of jaundice.
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Non-respiratory Functions of The Lungs
17:39
17:39
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17:39
The lungs not only allow us to breathe but also carry out many other vital functions.
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Introduction to the Respiratory System
21:22
21:22
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A general overview of the functions of the respiratory system and its various components.
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Foetal and Neonatal Circulation
33:48
33:48
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About the unique circulation in the foetus, the changes which occur after birth, and various possible congenital heart defects. For detailed notes, please visit my blog mentioned in the podcast description.
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About the blood flow to the brain.
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One of the most important things to know about in medicine, I talk about heart failure in this episode.
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The blood flow from the gut, spleen and pancreas to the liver together makes up the splanchnic circulation.
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By maintaining proper body fluid levels, the kidneys play the primary role in stabilising blood pressure in the long run.
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Short-term regulation of blood pressure
25:43
25:43
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25:43
As the title says, I talk about short-term regulation of blood pressure in this episode.
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One of the more devastating STIs.
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Sexually Transmitted Diseases: Part 1
24:45
24:45
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Sexually Transmitted Diseases (STDs) are something that we should all know more about. I give an overall introduction of the topic in this episode.
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It’s the impairment of the 7th cranial nerve or the facial nerve. Not that uncommon, it’s a relevant thing to talk about.
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A possibly fatal and often misdiagnosed condition, Addisonian’s disease is a must-know for all physicians.
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Just read this article on the Guardian about a promising study by researchers which suggest that fibromyalgia may be autoimmune in nature.
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Red Blood Cells: Structure, Parameters and Functions
26:40
26:40
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26:40
A first part in the series of RBCs.
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A brief overview of blood. I’m sorry, I forgot some important points that I should have mentioned, but as lazy as I am, I proceeded to upload this episode anyway.
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Arguably the most fundamental concept of the human body.
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A bit of an overview on malaria, the troublesome tropical infectious disease.
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An overview of the disease called Hodgkin’s Lymphoma.
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Parkinson’s Disease
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