“LA Made” is a series exploring stories of bold Californian innovators and how they forever changed the lives of millions all over the world. Each season will unpack the untold and surprising stories behind some of the most exciting innovations that continue to influence our lives today. Season 2, “LA Made: The Barbie Tapes,” tells the backstory of the world’s most popular doll, Barbie. Barbie is a cultural icon but what do you really know about her? Hear Barbie's origin story from the peopl ...
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เนื้อหาจัดทำโดย Alan Weiss's The Uncomfortable Truth® and Alan Weiss เนื้อหาพอดแคสต์ทั้งหมด รวมถึงตอน กราฟิก และคำอธิบายพอดแคสต์ได้รับการอัปโหลดและจัดหาให้โดยตรงจาก Alan Weiss's The Uncomfortable Truth® and Alan Weiss หรือพันธมิตรแพลตฟอร์มพอดแคสต์ของพวกเขา หากคุณเชื่อว่ามีบุคคลอื่นใช้งานที่มีลิขสิทธิ์ของคุณโดยไม่ได้รับอนุญาต คุณสามารถปฏิบัติตามขั้นตอนที่แสดงไว้ที่นี่ https://th.player.fm/legal
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A Conversation with Doug Durand
MP3•หน้าโฮมของตอน
Manage episode 419783269 series 1392109
เนื้อหาจัดทำโดย Alan Weiss's The Uncomfortable Truth® and Alan Weiss เนื้อหาพอดแคสต์ทั้งหมด รวมถึงตอน กราฟิก และคำอธิบายพอดแคสต์ได้รับการอัปโหลดและจัดหาให้โดยตรงจาก Alan Weiss's The Uncomfortable Truth® and Alan Weiss หรือพันธมิตรแพลตฟอร์มพอดแคสต์ของพวกเขา หากคุณเชื่อว่ามีบุคคลอื่นใช้งานที่มีลิขสิทธิ์ของคุณโดยไม่ได้รับอนุญาต คุณสามารถปฏิบัติตามขั้นตอนที่แสดงไว้ที่นี่ https://th.player.fm/legal
I met Doug at Merck where he worked as a sales executive and I was an external consultant. Some years later, he called me from his current pharma company and asked my advice about an ethical issue he was seeing. About five years later, he was presented with a huge (listen to find out how much) “whistleblowers award” for turning the dangerous practices in for the government to investigate and eliminate. We talk here about the courage and risks of being a whistleblower (two such people formerly employed by Boeing have since died, one by suicide, one by unknown causes, and Doug faced physical threats) and why they are needed more than ever today. We discuss whether drug prices are reasonable in light of the investment in creating them and, if efficacious, obtaining FDA approval. The results might surprise you. We also discuss the high mortality diseases, such as Alzheimer’s, diabetes, and cancer, and whether too much is spent on “cure” and treatment at the expense of investment in prevention. The issue of extending life, but with quality, is raised, as is the need for certain types of surgery being abandoned. Also examined is the ironic serendipity of drug creation, aside from huge, targeted investment, which we’ve seen result in weight loss, hair growth, and the eradication of African River Blindness. Sometimes, even with drugs, it’s better to be lucky than good. And don’t miss our focus on opioids and the absence of whistleblowers among people who should have acted but didn’t throughout this crisis.
…
continue reading
379 ตอน
MP3•หน้าโฮมของตอน
Manage episode 419783269 series 1392109
เนื้อหาจัดทำโดย Alan Weiss's The Uncomfortable Truth® and Alan Weiss เนื้อหาพอดแคสต์ทั้งหมด รวมถึงตอน กราฟิก และคำอธิบายพอดแคสต์ได้รับการอัปโหลดและจัดหาให้โดยตรงจาก Alan Weiss's The Uncomfortable Truth® and Alan Weiss หรือพันธมิตรแพลตฟอร์มพอดแคสต์ของพวกเขา หากคุณเชื่อว่ามีบุคคลอื่นใช้งานที่มีลิขสิทธิ์ของคุณโดยไม่ได้รับอนุญาต คุณสามารถปฏิบัติตามขั้นตอนที่แสดงไว้ที่นี่ https://th.player.fm/legal
I met Doug at Merck where he worked as a sales executive and I was an external consultant. Some years later, he called me from his current pharma company and asked my advice about an ethical issue he was seeing. About five years later, he was presented with a huge (listen to find out how much) “whistleblowers award” for turning the dangerous practices in for the government to investigate and eliminate. We talk here about the courage and risks of being a whistleblower (two such people formerly employed by Boeing have since died, one by suicide, one by unknown causes, and Doug faced physical threats) and why they are needed more than ever today. We discuss whether drug prices are reasonable in light of the investment in creating them and, if efficacious, obtaining FDA approval. The results might surprise you. We also discuss the high mortality diseases, such as Alzheimer’s, diabetes, and cancer, and whether too much is spent on “cure” and treatment at the expense of investment in prevention. The issue of extending life, but with quality, is raised, as is the need for certain types of surgery being abandoned. Also examined is the ironic serendipity of drug creation, aside from huge, targeted investment, which we’ve seen result in weight loss, hair growth, and the eradication of African River Blindness. Sometimes, even with drugs, it’s better to be lucky than good. And don’t miss our focus on opioids and the absence of whistleblowers among people who should have acted but didn’t throughout this crisis.
…
continue reading
379 ตอน
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