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This episode originally aired in January 2021 The story of how GameStop went from the verge of a bankruptcy to a $15 billion market value isn’t an easy one to wrap your head around. But it helps to go back to the beginning; almost three years ago, in a subreddit called r/wallstreetbets. Guests: Brandon Kochkodin, reporter at Bloomberg Learn more ab…
 
0:00 Bestie intro 1:14 Constitution DAO: implications, shortcomings, how to move forward? 29:58 Rittenhouse trial media coverage 50:52 Ken Griffin plays heel (again), private sector efficiency vs. government inefficiency 1:07:08 Pete Davidson's pull, Sacks' taste in music, wrap Follow the besties: https://twitter.com/chamath https://linktr.ee/calac…
 
Over the weekend, Russia tested a new weapon​​—a type of missile that can fly into space and destroy a satellite in orbit. The test created thousands of pieces of debris, which will hurtle around the Earth’s orbit for years to come. What’s the real risk of the rapid increase in space junk? And is there anything to be done about it? Guest: Laura Gre…
 
0:00 Bestie intro and Solana Breakpoint talk 4:43 Covering the censored segment from last week, how to value crypto projects and general investing, what to take away from the podcast 30:45 Rivian's >$100B valuation, greatest CNBC hit of all time 42:06 Inflation: reacting to the CPI number, problems with MMT, strategies to curb it 1:01:34 Xi Jinping…
 
A recent poll showed that about a third of parents of younger children would get their kids vaccinated, a third would not, and the final third said they wanted to wait and see how the vaccines worked. Public health officials are asking: what will it take to convince that third group that now is the time to vaccinate? Guests: Julie Hamill Dr. Aaron …
 
Show Notes: 0:00 Besties do a Microsoft-themed intro 7:53 Spread trading big tech, amazing power of Google and Microsoft 17:28 Sacks speaks about Bird going public from the NYSE, understanding distributions and evergreen funds, why Friedberg went the startup studio route 30:36 How DAOs fit in to the capital allocation landscape, the balance of cons…
 
In schools across the country, tighter digital controls were put in place to keep kids on task during the pandemic. Are they here to stay? Guests: Priya Anand, reporter at Bloomberg Host: Lizzie O’Leary Learn more about your ad choices. Visit megaphone.fm/adchoicesโดย Slate Podcasts
 
0:00 Bestie intro, child update, Joe Lonsdale’s take on paternity leave 20:44 Proposed “Wealth Tax” 35:13 Inflation discussion: corporate and government reactions 52:30 Dealing with inflation as a capital allocator 58:49 Big Tech’s outrageous quarterly earnings, why Google is the best business ever, Facebook’s “Meta” rebrand Follow the besties: htt…
 
The bots aren’t just buying cool sneakers. They’re buying concert tickets. Tickets to basketball games and Broadway shows. At the beginning of the pandemic, they were buying hand sanitizer and face masks. And later, they were booking vaccine reservation spots. Why are bots taking over certain markets? And is there anything we can do to slow them do…
 
Show Notes: 0:00 Bestie weight loss strategies, poker recap 13:19 Trump SPAC, how he can leverage the capital intelligently, building vs. acquiring, and more 33:43 Peak venture returns, tech landscape 44:56 Tech's global role: are we still in the early days, as opposed to a bubble? Wealth shaming, upward mobility 58:58 Democrats overplaying their h…
 
Between April and June of this year, Zillow bought nearly 4,000 homes. And they had no intention of holding onto them. The plan was to flip houses, often and at scale, joining the ranks of companies like Opendoor and Offerpad, also known as iBuyers. So, why did Zillow put their plans on pause last weekend? Can online middlemen really change the way…
 
Show Notes: 00:00 Cold Open 01:19 Titles 01:01 Intro Banter 04:24 Supply chain, labor shortage, 34:04 Taiwan 43:14 Sacks Desantis 47:00 Dave Chappelle 01:08:24 FDA 01:23:27 Question 1 01:27:08 Question 2 Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow th…
 
Over the last month, the domain company Epik and the streaming service Twitch have fallen prey to massive-scale hacks. The hackers revealed not just email addresses, but detailed personal information too. For Twitch, it was the entire source code for their site. But the attackers aren’t holding this data for ransom. In fact, they don’t seem to want…
 
Show Notes: 0:00 Mercury is in retrograde & impacting the besties 2:01 Sacks on Solana, sophisticated crypto strategies, crypto deep dive 26:23 Building regulatory framework for utility tokens, institutional money in crypto 40:59 Facebook whistleblower, potential ramifications & regulation 57:10 Comparing potential Facebook regulation to Microsoft …
 
The last month has seen a steady drip of leaked documents from inside Facebook, each seemingly more damning than the next. This week, the whistleblower behind the leaks revealed her identity. What motivates Frances Haugen? And can she do real damage to the social media giant? Guest: Jeff Horwitz, tech reporter at the Wall Street Journal. Host: Lizz…
 
Show Notes: 0:00 Brian Armstrong follows up on his one-year old blog post "Coinbase is a mission focused company" 19:27 Authoritarianism on the left 33:04 Newsom's new vaccine mandate, NBA vaccine coverage, Merck COVID pill 45:51 Golden Age of VC, 1000 unicorns & the impact on private/public markets 57:45 Corporate tax reform, Roth IRAs & the "Pete…
 
Since 2018, internal research teams at Facebook have been studying the effect on Instagram on mental health. Their results couldn’t be more clear: Instagram is causing problems, especially for teen girls. Why has it taken so long for their research to surface? And what can be done to improve the relationship between kids and the platform? Guest: Ge…
 
Show Notes: 0:00 Bestie Guestie Balaji Srinivasan is introduced 6:01 Balaji's day in the life, Coinbase background, comparing crypto with early 2000's p2p music industry, China's lawful evil 16:09 China declares crypto transactions illegal, comparing and contrasting the US and China's future outlook 39:43 Chances of a revolution in China, predictio…
 
In the U.S., the PCR test is the gold standard for COVID testing. Common knowledge would have it that the test is more accurate—and therefore more effective at containing the spread of the dease—than the rapid antigen test. What if that isn’t quite true? Guest: Michael Mina, assistant professor of epidemiology at the Harvard T.H. Chan School of Pub…
 
The final episode of Season 1 features Ted Ross, Chief Information Officer for the City of Los Angeles. His role became more vital than ever during the pandemic, with L.A.’s 4 million residents and 50,000 employees relying on the city’s complex technological operation for support. Ted helped his city navigate the challenge with tech solutions built…
 
Show Notes: 0:00 Besties intro, TPB Symposium recap, rapid generations in tech 7:00 UBI, incentives for success, social safety nets 19:45 Newsom's recall victory in California, where the GOP went wrong 33:59 Facebook's week from hell, Instagram's harmful impact on teen girls 42:42 How to properly regulate social media's impact on certain groups 1:0…
 
Recently, China restricted video game playing to just three hours a week for its young people: 8pm to 9pm, Friday through Sunday. And that’s not the only change. Over the last few months, private tutors, diehard celebrity fans, and tech giants have all faced fresh restrictions from Beijing. What’s behind this new wave of crackdowns? Guest: Brenda G…
 
Show Notes: 0:00 Open: LIVE from TPB Symposium 1:18 False Ivermectin story fools Rolling Stone, Rachel Maddow & more 15:47 Biden's recently announced vaccine mandates, why US hasn't been able to solve cheap testing 25:36 The threat of regulatory capture 34:18 Benefits of the "wartime mentality" when solving major issues 45:30 CCP looking to break u…
 
The Colorado River Basin is experiencing its 22nd year of drought. Its reservoirs are at their lowest-ever levels. The water stored in the system is at just 40 percent of its capacity. How did the situation on the Colorado become so dire? And what does the shortage mean for the 40 million people who rely on its waters? Guest: Abrahm Lustgarten, sen…
 
Show Notes: 00:00 Besties recap, it's Chamath's Birthday, Callin app 08:58 What should protocol be for conferences & live events? 12:58 Fake it before you make it, the Elizabeth Holmes Theranos trial & implications for fraud in VC 31:28 China's video game ban, is it a good move? 39:34 Texas Senate Bill 8, allowing suing for aiding an abetting abort…
 
A medicine meant to treat parasites is the latest unproven COVID treatment craze. With warnings from the FDA, and prescribers clamping down, some are going to extreme lengths to get their hands on the drug. What’s behind Ivermectin’s sudden rise? Guest: Brandy Zadrozny, senior reporter for NBC News Host: Lizzie O’Leary Learn more about your ad choi…
 
Show Notes: 0:00 Intro & Italy recap 12:06 An embarrassment in Afghanistan: breaking down how it happened 34:49 China's potential checkmate in Afghanistan, CCP cracking down on IPOs & algos 1:00:27 Rent moratorium ends, Prop 22 ruled unconstitutional, the shrinking role of agency 1:14:24 Boston Dynamics & TeslaBot, Bezos embarrasses himself with la…
 
Elizabeth Holmes convinced countless people that her company would change the world. Can she convince 12 jurors that she didn’t intend to deceive her company’s patients and investors? Guest: Rebecca Jarvis, host of “The Dropout” podcast and ABC News Chief Business, Technology & Economics Correspondent Host: Lizzie O’Leary Learn more about your ad c…
 
The Biden administration says a third dose of vaccines for all American adults will end the pandemic faster. And experts say there is evidence of waning vaccine effectiveness against mild-to-moderate disease. But globally, what’s the best use of the next available dose? Guest: Saad Omer, director of the Yale Institute for Global Health. Host: Lizzi…
 
Experts say that a “fully approved” designation for the vaccines could have sweeping effects. Broader vaccination mandates, inclusion for new age groups, and reassurance for those hesitant to take a vaccine without the designation. As calls for approval grow louder and more urgent, the Food and Drug Administration is yet to give its blessing. What’…
 
America used to be at the vanguard of railroad technology. What went wrong? And can the new infrastructure bill fix our broken system? Guests: Alon Levy and Eric Goldwyn of the Marron Institute at NYU Host Henry Grabar Learn more about your ad choices. Visit megaphone.fm/adchoicesโดย Slate Podcasts
 
Show Notes: 0:00 Big week for the besties: Friedberg's new raise, Sacks' new fund & more 16:30 Innovative venture strategies: internal mark ups, venture studios, deployment strategies 30:44 Zymergen's implosion: role of diligence, how to make deep tech sustainable, finding frauds 43:26 How personal risk impacts decision making on a grand scale, nar…
 
Whether it’s a phone screen or a coffee machine, why is it so hard to fix our own stuff? And what can we do to make it a bit easier? Guest: Jason Koebler, editor-in-chief of Motherboard and contributor to the CYBER podcast Host Lizzie O’Leary Learn more about your ad choices. Visit megaphone.fm/adchoices…
 
Show Notes: 0:00 Quick vaccine passports update 17:15 China's massive tech crackdown: reasons, ramifications, & more 37:37 How will large firms & institutional investors react to the CCP's recent regulatory moves, mechanics of delisting public companies 41:25 CRISPR breakthrough, future possibilities 50:18 Taking the right approach to climate chang…
 
This week, Amnesty International and a French journalism nonprofit named Forbidden Stories revealed that technology from a spyware firm called NSO Group is being deployed on a massive scale. The spyware, called Pegasus, gives the user access to every part of a victim’s smartphone -- notes, messages, photos, and recordings. What’s it like for securi…
 
Show Notes: 0:00 Intro & Dog update 5:48 COVID, Vaccine mandates, public vs. private policy 26:26 Collectivism, comparison to cigarettes, Sacks' latest podcast beef 36:56 Vaccine incentives in France 45:39 Friedberg's science corner: DeepMind's latest breakthrough, Big Tech censorship, free speech infringements 59:40 Capital's role in progress, Bez…
 
Over the last month, North Americans have seen record-breaking heat, droughts, wildfires, and floods. The science is clear: we are living through the effects of climate change. Now scientists are trying to answer: is this the new normal? Guest: Daniel Swain, climate scientist at UCLA Host Lizzie O’Leary Learn more about your ad choices. Visit megap…
 
Show Notes: 0:00 Bestie game show: Who got COVID? How was the experience? 9:30 Delta breakthrough causing concern, potential new approaches, vaccine mandates 24:26 Implications on the economy, will people self-isolate even without government shutdowns? 40:09 Billionaire Space Race: Addressing the negativity, benefits of innovators 47:29 Investments…
 
For many white-collar workers, the full-time work from home era is coming to an end. Some are going back into offices five days a week. Many others will be expected to split the week between home and the office. As the new rules are laid down, office workers are asking themselves: do we want work to go back to the way it was? Or is it time, finally…
 
Show Notes: 0:00 Super drought & climate crisis on the west coast 25:53 Nuclear energy, virtue signaling, cognitive laziness, positive signals of optimism 36:50 Friedberg's "anti-science" theory 44:48 San Francisco chaos, "crime is down" controversy, viral crime videos 59:42 Are Israel's recent COVID vaccine findings problematic? Follow the besties…
 
From Slate Studios & ServiceNow, this episode of Let’s Workflow It features Deryck Mitchelson – one of the leaders taking on the greatest workflow challenge of our time – the effort to vaccinate millions of citizens from COVID-19. As Director of Information Security for NHS National Services Scotland, Deryck manages his nation’s contact tracing and…
 
Show Notes: 0:00 Jason & Sacks hash out their Twitter beef 20:58 Robinhood $70M FINRA fine signals & S-1 news, plus how GPs think about IPO distributions 35:29 Delta variant: reason for concern or fear porn? 57:25 Trump not taking credit for Project Lightspeed, Trump CFO indicted, will Dems prosecuting Trump backfire & help him gain steam for 2024?…
 
Last week, the U.S. government released a new report that attempts to categorize 144 verified sightings of unidentified aerial phenomena, or UAP. They could only definitively explain one of them. The new report signals a shift in the way we think about UAP. As technology has advanced and evidence of these encounters has increased, the question has …
 
For nearly two years, an unprecedented experiment has been taking place in the town of El Zonte in El Salvador. Funded by a mysterious donor, the town’s residents built a Bitcoin economy, using the cryptocurrency to purchase just about anything. Now, El Slavador has passed a new law making it the first country to adopt Bitcoin as legal tender. Can …
 
Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Referenced in the show: NYT - N.Y.C. Mayoral Race Highligh…
 
Ever since police used a DNA platform called GEDmatch to crack the Golden State Killer case in 2018, police departments around the country have rushed to use genetic genealogy to crack their own cold cases. The result? Hundreds of violent cases solved. So--why are some states passing new laws to limit this new technology? Guest: Nila Bala, senior s…
 
Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Show Notes: 00:00 Besties intro 03:37 Lina Khan appointed …
 
Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Show Notes: 0:00 Bestie intro, Chamath's whereabouts 2:54 Breaking down Biogen's Alzheimer's drug & the FDA's controversial approval 2…
 
Over the last decade, billionaires like Jeff Bezos, Elon Musk, and Richard Branson have come to embody the future of space travel and exploration. What does it mean when the ideas and ambitions of a few powerful men come to dominate the conversation so thoroughly? Guest: Lucianne Walkowicz, astronomer at the Adler Planetarium and founder of the Jus…
 
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