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NEJM This Week

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Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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NEJM Interviews

NEJM Group

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Insightful conversations with leading experts in the field of health care, medical research, policy, and more from the New England Journal of Medicine (NEJM). Each episode examines the many complexities found at the junction of medicine and society.
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NEJM AI Grand Rounds

NEJM Group

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NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations w ...
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Heather Hsu is a pediatric hospitalist at Boston Medical Center and an assistant professor of pediatrics at the Boston University Chobanian and Avedisian School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. K.A. Nash, J. Perdomo, and H.E. Hsu. Health Equity Rounds — Root-Cause and Solutions-Orient…
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Featuring articles on perioperative durvalumab in bladder cancer, transcatheter valve repair for mitral regurgitation, chemoradiotherapy in gastric cancer, and lessons from England’s National Health Service; a review article on lung transplantation; a case report of a newborn with hypoxemia and a lung opacity; and Perspectives on our latest brief c…
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Vincent Guilamo-Ramos is the executive director of the Institute for Policy Solutions at the Johns Hopkins School of Nursing. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. V. Guilamo-Ramos, M. Thimm-Kaiser, and A. Benzekri. The U.S. Latino HIV Crisis — Ending an Era of Invisibility. N Engl J Med 2024;391:1665-…
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Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Sabin Nsanzimana, M.D., Ph.D., is the Minister of Health of Rwanda. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin and Others. Audio Interview: The Marburg Virus Outbreak in Rwanda. N Engl J Med 2024;39…
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Featuring articles on an invasive treatment strategy in older patients with myocardial infarction, a randomized trial of very early medication abortion, therapies in stage III melanoma, and on long Covid defined; a review article on uterine fibroids; a Clinical Problem-Solving on two sides to the story; and Perspectives on the U.S. Latino HIV crisi…
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Liam McCoy is a resident physician in neurology at the University of Alberta. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. L.G. McCoy, A.K. Manrai, and A. Rodman. Large Language Models and the Degradation of the Medical Record. N Engl J Med 2024;391:1561-1564.
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Featuring articles on semaglutide in persons with obesity and knee osteoarthritis, the addition of PI3K inhibition in breast cancer, treatments in older patients with myeloma, and total hip replacement for hip osteoarthritis; a review article on lead poisoning; a case report of a man with dyspnea after old myocardial infarction; and Perspectives on…
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Mark Wicclair is an adjunct professor of medicine at the University of Pittsburgh Center for Bioethics and Health Law and a professor of philosophy emeritus at West Virginia University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.B. White and M. Wicclair. Navigating Clinicians’ Conscience-Based Refusals to…
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Featuring articles on treatments in heart failure, advanced non–small-cell lung cancer, and Dupuytren’s contracture; a neurodevelopmental disorder caused by deletion in a long noncoding RNA; a review article on burnout and depression among physicians; a case report of a woman with confusion, aphasia, and a brain mass; a Medicine and Society article…
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Jose Figueroa is an associate professor of health policy and management at the Harvard T.H. Chan School of Public Health and an assistant professor of medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.M. McWilliams and S.B. Dusetzina. Affordability of Health Care in the United…
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Featuring articles on nivolumab in advanced Hodgkin’s lymphoma, kidney transplantation from donors with HIV, a modular communicative leadless pacing–defibrillator system, stereotactic body radiotherapy in prostate cancer, and on how DNA sensing drives inflammation; a review article on cryoglobulinemia; a case report of a woman with dyspnea, dysphag…
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In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. David Ouyang, a cardiologist and AI researcher at Cedars-Sinai Medical Center. The conversation explores Ouyang’s journey from medical training to AI research and entrepreneurship, his groundbreaking work in applying AI to cardiology imaging, and the challenges of…
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Jean Nachega is an associate professor of infectious diseases and microbiology and of epidemiology at the University of Pittsburgh School of Public Health and a professor of medicine at Stellenbosch University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.B. Nachega and Others. Mpox in Pregnancy — Risks, Ve…
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Featuring articles on beta-blocker use after myocardial infarction and treatments for cerebral adrenoleukodystrophy and for small-cell lung cancer; a review article on hairy-cell leukemia; a case report of a man with fever, myalgia, jaundice, and respiratory failure; and Perspectives on Mpox, on addressing health care cost growth, and on confirmato…
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Jonathan Oberlander is a professor of social medicine and of health policy and management at the University of North Carolina at Chapel Hill. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J. Oberlander. Health Care Reform and the 2024 U.S. Elections — Low Visibility, High Stakes. N Engl J Med 2024;391:1169-117…
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Featuring articles on lenacapavir for HIV prevention in cisgender women, tirzepatide for treatment of obstructive sleep apnea, lymphadenectomy for muscle-invasive bladder cancer, secondary T-cell lymphoma after CAR T-cell therapy, and immunity and early colorectal carcinogenesis; a review article on prolonged grief disorder; a Clinical Problem-Solv…
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Abigail Cutler is an assistant professor and associate residency program director in the Department of Obstetrics and Gynecology at the University of Wisconsin School of Medicine and Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.S. Cutler and E. Hartenbach. Dobbs Revisited — Addressing Effects…
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Featuring articles on systematic vs. targeted biopsy for prostate cancer screening, ziresovir in hospitalized infants with RSV, gene therapy for factor IX deficiency, and a phase 2 trial of tulisokibart for ulcerative colitis; a review article on neuroleptic malignant syndrome; a case report of a woman with kidney lesions and lytic bone disease; an…
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Charles Weijer is a professor in the Departments of Medicine and Philosophy at Western University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. C. Weijer and M. Taljaard. Ethical Challenges Associated with Pragmatic and Cluster RCTs. N Engl J Med 2024;391:969-971.…
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Featuring articles on long-term oxygen therapy in severe hypoxemia, reducing opioid overdose deaths, blocking CSF1R in chronic GVHD, and pomalidomide in hereditary hemorrhagic telangiectasia; a review article on central nervous system vasculitis; a case report of a man with confusion and kidney failure; a Medicine and Society on house staff unioniz…
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In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Noa Dagan and Dr. Ran Balicer from the Clalit Research Institute in Israel. The conversation explores Clalit’s groundbreaking work in implementing predictive models at the point of care, their contributions to COVID-19 research, and the potential of AI in revoluti…
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Did you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.
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Did you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.
  continue reading
 
Did you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.
  continue reading
 
Did you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.
  continue reading
 
Did you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.
  continue reading
 
Did you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.
  continue reading
 
Did you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.
  continue reading
 
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