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Epidemics and Vaccines
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Epidemics and Vaccines

Oxford University

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Vaccines save millions of lives each year; however, some of the world's worst diseases are still difficult to prevent. Our series of podcasts on Epidemics and Vaccines detail the research within NDM to combat diseases such as hepatitis, influenza and tuberculosis, through development of novel vaccines and vaccine delivery mechanisms and strategies. Developing countries and vulnerable populations are a particular focus of some of this work.
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Professor Peter Horby is Senior Clinical Research Fellow. His research focusses on epidemic diseases such as Ebola and bird flu, and crosses the disciplines of basic science, medical science and public health. Influenza, SARS & EbolaResearch on emerging infectious diseases can only be conducted during outbreaks. Although virology has improved, a we…
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Structure of viruses Professor David Stuart studies the structure of viruses at the molecular level. His work is particularly interested in virus-receptor interaction and the basic puzzles of virus assembly and he uses structural biology to answer these questions.โดย Dave Stuart
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Dr Jan Rehwinkel talks about the role of our innate immune system in our fight against flu virus. The innate immune response is critical for a successful defence against viral infection. The first arm of our immune response is triggered by the detection of the presence of the virus: cell surface receptors detect the presence of viral genomic inform…
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Professor Sarah Gilbert talks about her work on viral vectored vaccines. Viral vectored vaccines combine a safe virus with a disease protein to protect against specific diseases. These vaccines have the potential to drastically improve public health. Professor Sarah Gilbert has been making and testing vaccines designed to induce T cell responses fo…
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Dr Richard Antrobus talks about his research in the development of a universal flu vaccines. Universal flu vaccines target specific parts of the influenza virus that stay relatively stable between different strains of flu. Dr Richard Antrobus is conducting a Phase I study for a universal influenza vaccine. Progress so far indicates that this approa…
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Dr Helen Fletcher talks about progress in the development of a vaccine against tuberculosis. Tuberculosis kills two million people annually, with the majority of infection occurring in developing countries. Dr Helen Fletcher works on multi-partner projects to discover biomarkers of protection from TB disease, develop clinical trials capacity in Afr…
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Dr Ellie Barnes talks about her research on Hepatitis C and her work on a T cell vaccine. Hepatitis C virus is a global epidemic, affecting around 200 million people worldwide. Many chronically infected patients silently develop complications of liver disease that can include hepatocellular cancer, liver cirrhosis and liver failure. Unlike other va…
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Professor Paul Klenerman talks about our relationship with persistent viruses, such as Hepatitis C. Hepatitis C virus infects around 200 million people worldwide and is a major cause of liver disease. Understanding immune responses to the virus could help to protect or cure people with Hepatitis C. Professor Paul Klenerman studies relationships bet…
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Professor Helen McShane talks about her work on a new vaccine against tuberculosis. There are about 9 million new cases and two million deaths every year from tuberculosis (TB). BCG, now over 100 years old, remains the only licensed vaccine against TB. It confers good protection against severe disease and meningitis, but doesn't protect against lun…
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